Recruiting

Observational Study

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06907706

Conditions

Cancer

Fatigue

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Physical Activity/Physical Functioning

Quality of Life

Study Details

Brief summary:

The goal of this research study is to learn more about a physical activity program adapted for cancer survivors.

Conditions

Cancer

Fatigue

Study ID

NCT06907706

Start date

Apr 3, 2023

Status verified date

May, 2026

Completion date

Apr 30, 2029

Anticipated

Primary completion date

Apr 30, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Past diagnosis of invasive cancer, or a caregiver (family or friend) of a participating survivor.
2. No longer receiving treatment for cancer (except hormone therapy or long-term maintenance chemotherapy).
3. Over the age of 18.
4. Screen negative for contraindicating health problems on the adapted Physical Activity Readiness Questionnaire (PAR-Q),79 or screened positive but have approval from a health care provider to participate.
5. Lives in the Acres Homes neighborhood of Houston, Texas or has a home zip code of 77088 or 77091.
6. Able to provide informed consent.

Exclusion Criteria:

1. Women who are pregnant (as indicated by self-report).
2. Has participated in the ALAC program within the past year and attended more than 2 group sessions.

Study Design

Enrollment

164 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Intervention

Receives the ALAC intervention following the baseline assessment

active comparator: Waitlist Control

Receives the ALAC intervention following the 3-month assessment

Interventions

Physical Activity/Physical Functioning

The physical activity portion of the program sessions focuses on teaching cognitive and behavioral skills to increase physical activity, including goalsetting, self-monitoring, overcoming barriers to physical activity, enlisting social support, and how to handle "high risk" situations that may result in relapses to a sedentary lifestyle. The health educator teaches participants about various forms of moderate intensity activity and has them practice brief bouts of activity of various types to ensure that they are doing the activities safely and correctly. Each week participants receive a handout to provide information about the behavioral skill taught that week. The program also provides activity trackers (week 1) and resistance bands (week 5). The pedometer assists participants in self-monitoring their activity, and the resistance bands provide a form of home-based exercise that participants can do even with limited space.

Quality of Life

The survivorship portion of the program features a guided discussion on a different topic each session. The goals of the discussion are to present information about the topic, answer participants' questions about the topic, encourage participants to share solutions and ideas relevant to the topic with each other, and provide information on community resources participants can access if they require additional help. The health educator makes a brief presentation about the topic, answers questions, and then asks a series of 2-3 open-ended questions to facilitate discussion about the topic. At the end of the session, the health educator navigates participants who need additional information or service related to the topic to resources in the community.

Primary outcome measure

  • Re-AIM Framework [ Time Frame: Through study completion; an average of 1 year. ]

Central Contacts and Locations

Central contacts

Karen Basen-Engquist, BA,MPH,PHD

(713) 745-3123kbasenen@mdanderson.org

Locations

The University of Texas M. D. Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77090

Contacts

Karen Basen-Engquist, BA,MPH,PHD

713-745-3123kbasenen@mdanderson.org

Principal Investigator:

Karen Basen-Engquist, BA,MPH,PHD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Jun 1, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-06-01.