Recruiting

Treatment for DLD

Sponsor:

Ohio University

Code:

NCT06911138

Conditions

Developmental Language Disorders

Eligibility Criteria

Sex: All

Age: 8 - 11

Healthy Volunteers: Not accepted

Interventions

Behavorial

Study Details

Brief summary:

The goal of this project is to compare the relative effectiveness of two novel treatments to improve the complex grammar knowledge of school-age (8-11-year-old) children with developmental language disorder (DLD). Treatment 1 is an implicit approach to promoting children's automatic grammar learning and Treatment 2 is a more conventional explicit approach in which participants are taught the rules underlying the grammar. Treatment 1 involves children listening to an examiner produce a target sentence 20 times during each training session while describing a picture. The children will then see a picture and be asked to describe the action taking place. Treatment 2 involves children listening to an examiner describe the action occurring in a picture using a sentence pattern targeted to the child's deficit. The child will then be asked who did the action in the sentence and who received the action, after which the examiner will provide specific feedback about why the child's response was correct or incorrect. The expectation is that over a short period children will begin to use their targeted sentence pattern after hearing the examiner produce it many times.

Children will complete four outcome measures (syntactic knowledge, sentence comprehension, sentence chunking, narrative comprehension/ production) prior to treatment, immediately after treatment, and five weeks after treatment. Children will be randomly assigned to one of the two treatments. Both treatments will be delivered 20 times over 10 weeks. The investigators anticipate that the children receiving Treatment 1 will show stronger gains in knowledge across the four outcome measures.

Conditions

Developmental Language Disorders

Study ID

NCT06911138

Start date

Dec 1, 2024

Status verified date

Dec, 2024

Completion date

Oct 15, 2027

Anticipated

Primary completion date

Aug 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 8 - 11

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Language impairment: standard score of 34 or lower on the Test of Language and Learning Skills
  • Nonverbal IQ: nonverbal quotient of 77 or higher
  • Normal range hearing
  • Normal or corrected vision
  • Native English speaker
  • Sentence comprehension screening/sentence chunking screening 50% or lower

Exclusion Criteria:

  • Neurodevelopmental disorder
  • Emotional/behavioral disorder
  • Frank neurological disorder
  • Treatment for complex syntax from outside clinician

Study Design

Enrollment

150 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Implicit Immediate Treatment

This treatment involves providing participants an implicit approach to grammar learning via a syntactic priming paradigm immediately following the completion of the pre-treatment measures.

experimental: Implicit Delayed Treatment

This treatment involves providing participants an implicit approach to grammar learning via a syntactic priming paradigm 10 weeks following the completion of the pre-treatment measures. This arm allows assessing whether improvement on the outcome measures is due to 10 weeks of treatment or just maturation.

experimental: Explicit Immediate Treatment

This treatment involves providing participants an explicit approach to grammar learning via conventional teaching of grammatical rules immediately following the completion of the pre-treatment measures.

experimental: Explicit Delayed Treatment

This treatment involves providing participants an explicit approach to grammar learning via conventional teaching of grammar rules 10 weeks following the completion of the pre-treatment measures. This arm allows assessing whether improvement on the outcome measures is due to 10 weeks of treatment or just maturation.

Interventions

Behavorial

Behavioral intervention that focuses on improving syntactic knowledge.

Primary outcome measure

  • Sentence Comprehension [ Time Frame: Comprehension is assessed at baseline and twice at post-test, immediately following treatment and up to 5 weeks post-treatment. ]
  • Sentence Priming [ Time Frame: Syntactic knowledge is assessed at baseline and twice at post-test, immediately following treatment and up to 5 weeks post-treatment. ]
  • Sentence Chunking [ Time Frame: Sentence chunking is assessed at baseline and twice at post-test, immediately following treatment and up to 5 weeks post-treatment. ]
  • Narrative Comprehension/Retell [ Time Frame: Narrative comprehension/retell is assessed at baseline and twice at post-test, immediately following treatment and up to 5 weeks post-treatment. ]
  • Working Memory [ Time Frame: Working memory is assessed at baseline and twice at post-test, immediately after treatment and up to 5 weeks post-treatment. ]

Central Contacts and Locations

Central contacts

Locations

University of Arizona

Recruiting

Tucson, Arizona, United States, 85721

Contacts

Ohio University

Recruiting

Athens, Ohio, United States, 45701

Contacts

Utah State University

Recruiting

Logan, Utah, United States, 84322

Contacts

West Virginia University

Recruiting

Morgantown, West Virginia, United States, 26506

Contacts

More Information

Sponsor

Ohio University

Last update posted

Apr 4, 2025

Last verified

Dec, 2024

Keywords

  • Treatment

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Ohio University on 2025-04-04.