Recruiting

Observational Study

Sponsor:

Seattle Children's Hospital

Code:

NCT06932432

Conditions

Chronic Pain

Eligibility Criteria

Sex: All

Age: 18 - 25

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The goal of this observational study is to determine real-time contextual vulnerabilities associated with pain in young adults to inform ideal treatment targets for a just-in-time adaptive intervention (JITAI). The main question it aims to answer is:

-What contextual factors and vulnerabilities will predict momentary, next-day, and weekly pain severity? 50 young adults, ages 18-25 with a diagnosis of childhood-onset primary chronic pain, will complete 1) baseline questionnaires on REDCap to collect data on sociodemographics, medical history and treatment, psychological health (i.e., current mood symptoms and previous psychiatric conditions/treatment), and pain (e.g., duration, location) and 2) a 28-day EMA via mobile app to collect survey data on dynamic factors.

Conditions

Chronic Pain

Study ID

NCT06932432

Start date

Dec 1, 2024

Status verified date

Apr, 2025

Completion date

Dec, 2027

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 25

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • ages 18-25
  • diagnosis of childhood-onset chronic pain who were seen for an initial evaluation at Seattle Children's Hospital outpatient specialty clinics.

Exclusion Criteria:

  • not fluent in English
  • does not have regular access to the internet and access to a smartphone device (to complete EMA questions)
  • presence of chronic disease or serious medical illness (e.g., arthritis, cancer, diabetes)
  • serious cognitive impairment or developmental disorder (e.g., autism, intellectual disability)

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Momentary Pain intensity [ Time Frame: Three times a day for 28 days ]
  • Momentary Pain interference [ Time Frame: Three times a day for 28 days ]

Central Contacts and Locations

Central contacts

Caitlin Murray, PhD

206-884-0147caitlin.murray@seattlechildrens.org

Locations

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States, 98101

Contacts

Caitlin Murray, PhD

206-884-0147caitlin.murray@seattlechildrens.org

More Information

Sponsor

Seattle Children's Hospital

Last update posted

Apr 27, 2025

Last verified

Apr, 2025

Keywords

  • EMA study
  • childhood onset chronic pain
  • Young adult
  • Cannabis use
  • Real-time predictors
  • Health outcomes

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Seattle Children's Hospital on 2025-04-27.