Recruiting

Observational Study

Sponsor:

Yale University

Code:

NCT06933875

Conditions

Heart Failure

Palliative Care

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Clinical Decision Support Tool

Study Details

Brief summary:

This project will develop and test a novel clinical decision support tool (CDS) that encourages timely referral to palliative care for people hospitalized with heart failure. This intervention will incorporate an existing, validated 1-year mortality risk model into a CDS to deliver prognostic information and evidence-based decision support at the point of care. Thus, this research may lead to improved care-concordant and goal-directed care for people with heart failure.

Conditions

Heart Failure

Palliative Care

Study ID

NCT06933875

Start date

Jul 2, 2026

Status verified date

Jul, 2026

Completion date

Oct 30, 2027

Anticipated

Primary completion date

Oct 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Healthcare providers must meet the following criteria:

  • Are an attending physician, fellow, or resident, advanced practice nurse, or physician associate
  • Has ordering privileges
  • Are members of one of the hospitals' admitting teams (e.g., hospitalist service, cardiology service)
  • Anticipate employment at one of the two study sites for the 15-month trial period.

Or

  • Palliative care team member
  • Hospital administrator/quality and safety personnel

Patients of providers enrolled in the study must meet the following criteria for heart failure during hospitalization:

  • Age 18 years of age or older
  • N-terminal pro-B-type natriuretic peptide values of >500 pg/ml
  • Received intravenous diuretics within 24 hours of admission.

Exclusion Criteria:

  • Pregnant at the time of admission.

Study Design

Enrollment

2260 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Clinical Decision Support (CDS) Tool

Patients will be randomized to have the CDS tool to deliver prognostic information and evidence-based decision support at the point of care for timely referral to palliative care for participants hospitalized with heart failure.

no intervention: Standard of Care

Providers will provide usual standard of care for participants hospitalized with heart failure.

Interventions

Clinical Decision Support Tool

Deliver prognostic information and evidence-based decision support at the point of care

Primary outcome measure

  • Mean System Usability Scale score [ Time Frame: up to 15 months ]
  • Mean Acceptability of Intervention Measure score [ Time Frame: up to 15 months ]
  • Mean Appropriateness of Intervention Measure score [ Time Frame: up to 15 months ]
  • Mean Feasibility of Intervention Measure score [ Time Frame: up to 15 months ]

Central Contacts and Locations

Central contacts

Shelli Feder, PhD

937-239-2801shelli.feder@yale.edu

Nathan Wright, MA

nathan.wright@yale.edu

Locations

Yale New Haven Hospital Saint Raphael

Recruiting

New Haven, Connecticut, United States, 06520

Yale New Haven Hospital York Street

Recruiting

New Haven, Connecticut, United States, 06520

More Information

Sponsor

Yale University

Last update posted

Jul 16, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Yale University on 2026-07-16.