Recruiting

Guided Meditation vs. Silence

Sponsor:

Ohio State University Comprehensive Cancer Center

Code:

NCT06949943

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Behavioral Intervention

Behavioral Intervention

Electronic Health Record Review

Survey Administration

Study Details

Brief summary:

This clinical trial tests how well guided meditation, compared to silence, works to reduce pre-operative anxiety in patients undergoing cancer-directed surgery. Pre-operative anxiety affects patient experience and has been found to be a predictor of severe post-operative pain and chronic pain after surgery, influencing the success and quality of a patient's recovery. While medication is often prescribed to improve anxiety symptoms, research has showed that mindfulness techniques can be used to decrease anxiety, improve comfort, and can impact both psychological and physiologic symptoms. Completing pre-operative guided meditation may work well to reduce pre-operative anxiety in patients undergoing cancer directive surgery.

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Study ID

NCT06949943

Start date

Mar 14, 2025

Status verified date

May, 2026

Completion date

Jul 31, 2027

Anticipated

Primary completion date

Jul 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Participants will be recruited among patients who are scheduled for cancer-directed surgery
  • Participants must be 18 years or older

Exclusion Criteria:

  • Participants will be excluded from the study if they cannot speak English (as the meditation is recorded in English)
  • Currently incarcerated
  • Have a diagnosis of dementia
  • Are admitted to the intensive care unit (ICU)
  • Have a hearing impairment that would make them unable to hear the recorded meditation

Study Design

Enrollment

300 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Arm I (guided meditation)

Patients listen to 10 minutes of guided meditation prior to surgery.

active comparator: Arm II (noise cancelling headphones)

Patients wear noise cancelling headphones for 10 minutes prior to surgery.

Interventions

Behavioral Intervention

Listen to guided meditation

Behavioral Intervention

Wear noise cancelling headphones

Electronic Health Record Review

Ancillary studies

Survey Administration

Ancillary studies

Primary outcome measure

  • Pre-operative anxiety (PROMIS Anxiety scale) [ Time Frame: Pre and post intervention, approximately 10 minutes ]
  • Pre-operative anxiety (single-item visual analog scale) [ Time Frame: Pre and post intervention, approximately 10 minutes ]

Central Contacts and Locations

Central contacts

The Ohio State University Comprehensive Cancer Center

800-293-5066OSUCCCClinicaltrials@osumc.edu

Locations

Ohio State University Comprehensive Cancer Center

Recruiting

Columbus, Ohio, United States, 43210

Contacts

Maryanna Klatt, PhD

614-366-1056Maryanna.Klatt@Osumc.edu

Principal Investigator:

Maryanna Klatt, PhD

More Information

Sponsor

Ohio State University Comprehensive Cancer Center

Last update posted

May 7, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Ohio State University Comprehensive Cancer Center on 2026-05-07.