Recruiting

Memory Rehabilitation

Sponsor:

University of British Columbia

Code:

NCT06956417

Conditions

Concussion, Brain

Mild Traumatic Brain Injury

Eligibility Criteria

Sex: All

Age: 18 - 59

Healthy Volunteers: Not accepted

Interventions

Cognitive behavioral therapy

Cognitive rehabilitation

Study Details

Brief summary:

Persistent memory symptoms after concussion are common, and likely perpetuated by unhelpful illness beliefs and coping behaviors. Results from a pilot study suggested that traditional cognitive rehabilitation and a novel cognitive-behavioral therapy (CBT) protocol were both associated with improvements in subjective memory functioning. The present study will more definitively compare the effectiveness of these interventions for improving subjective memory functioning after concussion.

Conditions

Concussion, Brain

Mild Traumatic Brain Injury

Study ID

NCT06956417

Start date

Jul 2, 2025

Status verified date

May, 2026

Completion date

Apr 30, 2029

Anticipated

Primary completion date

Apr 30, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 59

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Age 18-59
2. Concussion diagnosis confirmed with structured interview based on American Congress of Rehabilitation Medicine diagnostic criteria
3. Concussion occurred between 6 and 36 months before enrollment
4. Ongoing memory concerns
5. Fluent in English
6. Stable access to a computer, tablet, or smartphone with internet capability

Exclusion Criteria:

1. Fail performance validity testing
2. Comorbid psychiatric or neurological disorder or is taking a medication that could fully account for their memory symptoms

Study Design

Enrollment

184 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Cognitive behavioral therapy

active comparator: Cognitive rehabilitation

no intervention: Waitlist - Usual care

Interventions

Cognitive behavioral therapy

Cognitive behavioral therapy (CBT) is delivered by a psychologist over 10 individual (1:1) manualized videoconference sessions. The goal of this therapy is for participants to use their memory more normally (i.e., reduce avoidance and safety behaviors) and view memory lapses as less threatening.

Cognitive rehabilitation

Cognitive compensatory strategy training (CCST), a traditional cognitive rehabilitation intervention, is delivered by a Occupational Therapist over 10 individual (1:1) manualized videoconference sessions. Participants optimize their use of current compensatory strategies and/or learn new ones suited to their needs and lifestyle. The goal is to minimize memory lapses in daily life.

Primary outcome measure

  • Multifactorial Memory Questionnaire-Satisfaction scale [ Time Frame: Week 20 ]

Central Contacts and Locations

Central contacts

Noah D Silverberg, PhD

6047341313noah.silverberg@ubc.ca

Tasha L Klotz, BA

6047341313tasha.klotz@ubc.ca

Locations

Calgary Brain Injury Program

Recruiting

Calgary, Alberta, Canada, T2N 2T9

Contacts

Chantel Debert

chantel.debert@albertahealthservices.ca

Christina Campbell

christina.campbel1@ucalgary.ca

Fraser Health Acquired Brain Injury and Concussion Services

Recruiting

Langley, British Columbia, Canada, V1M 4A6

Contacts

William Panenka

will.panenka@ubc.ca

G.F. Strong Adult Concussion Services

Recruiting

Vancouver, British Columbia, Canada, V5Z 2G9

Contacts

Sarah Courtice

604-734-4113Sarah.Courtice@vch.ca

360 Concussion Care Clinic

Recruiting

Ottawa, Ontario, Canada, K1H 7X7

Contacts

Roger Zemek

1-613-668-0360roger.zemek@360concussioncare.com

Sunnybrook Traumatic Brain Injury Clinic

Recruiting

Toronto, Ontario, Canada, M4N 3M5

Contacts

Matthew Burke

matthew.burke@sunnybrook.ca

Hull-Ellis Concussion and Research Clinic at University Health Network

Recruiting

Toronto, Ontario, Canada, M5G 2A2

Contacts

Mark Bayley

mark.bayley@uhn.ca

Tharshini Chandra

(416) 597-3422tharshini.chandra@uhn.ca

Canadian Concussion Centre at Toronto Western Hospital

Recruiting

Toronto, Ontario, Canada, M5T 2S8

Contacts

Carmela Tartaglia

416-603-5483carmela.tartaglia@uhn.ca

Artee Srivastava

Artee.Srivastava@uhn.ca

More Information

Sponsor

University of British Columbia

Last update posted

Jun 2, 2026

Last verified

May, 2026

Keywords

  • Functional cognitive disorder

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of British Columbia on 2026-06-02.