Sponsor:
GlaxoSmithKline
Code:
NCT06959095
Conditions
Pulmonary Disease, Chronic Obstructive
Eligibility Criteria
Sex: All
Age: 40 - 70+
Healthy Volunteers: Not accepted
Interventions
Depemokimab
Placebo
Brief summary:
Conditions
Pulmonary Disease, Chronic Obstructive
Study ID
NCT06959095
Start date
Jun 20, 2025
Status verified date
Sep, 2026
Completion date
Feb 14, 2029
Anticipated
Primary completion date
Dec 13, 2028
Anticipated
Eligibility Criteria
Sex: All
Age: 40 - 70+
Healthy Volunteers: Not accepted
Enrollment
981 participants
Anticipated
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary purpose
Treatment
Arms
experimental: Depemokimab
placebo comparator: Placebo
Interventions
Depemokimab
Placebo
Primary outcome measure
Central contacts
Locations
GSK Investigational Site
Recruiting
Bakersfield, California, United States, 93301
Contacts
Principal Investigator:
Tonny Tanus
GSK Investigational Site
Recruiting
Modesto, California, United States, 95355-4046
Contacts
Principal Investigator:
Jose Rodriguez
GSK Investigational Site
Recruiting
Newport Beach, California, United States, 92663
Contacts
Principal Investigator:
Ryan Klein
GSK Investigational Site
Recruiting
Wilmington, Delaware, United States, 19803
Contacts
Principal Investigator:
Carole Guy
GSK Investigational Site
Recruiting
Bradenton, Florida, United States, 34209
Contacts
Principal Investigator:
Patrick Weston
GSK Investigational Site
Recruiting
Brandon, Florida, United States, 33511-5706
Contacts
Principal Investigator:
Rafael Martinez
GSK Investigational Site
Recruiting
Hialeah, Florida, United States, 33012
Contacts
Principal Investigator:
Alberto Manzor
GSK Investigational Site
Recruiting
Hialeah, Florida, United States, 33016
Contacts
Principal Investigator:
Juan Fernandez
GSK Investigational Site
Recruiting
Loxahatchee Groves, Florida, United States, 33470
Contacts
Principal Investigator:
Neal Warshoff
GSK Investigational Site
Recruiting
Miami, Florida, United States, 33126
Contacts
Principal Investigator:
Anish Dhadwal
GSK Investigational Site
Recruiting
Miami, Florida, United States, 33155
Contacts
Principal Investigator:
Guillermo Somodevilla
GSK Investigational Site
Recruiting
Miami Lakes, Florida, United States, 33016
Contacts
Principal Investigator:
Maria Elena Ocasio
GSK Investigational Site
Recruiting
Orange City, Florida, United States, 32763
Contacts
Principal Investigator:
Kristyna Paradis
GSK Investigational Site
Recruiting
Palm Springs, Florida, United States, 33406
Contacts
Principal Investigator:
Luis Castillo Hernandez
GSK Investigational Site
Recruiting
Palmetto Bay, Florida, United States, 33176-7296
Contacts
Principal Investigator:
Michael Feldman
GSK Investigational Site
Recruiting
Pensacola, Florida, United States, 32503-2698
Contacts
Principal Investigator:
Peter Bercz
GSK Investigational Site
Recruiting
Tamarac, Florida, United States, 33321
Contacts
Principal Investigator:
Neena Chandrasekaran
GSK Investigational Site
Recruiting
Tampa, Florida, United States, 33614
Contacts
Principal Investigator:
GERMAN ALVAREZ
GSK Investigational Site
Recruiting
The Villages, Florida, United States, 32162
Contacts
Principal Investigator:
Angela Okolie
GSK Investigational Site
Recruiting
Riverdale, Georgia, United States, 30274
Contacts
Principal Investigator:
Deon Miller
GSK Investigational Site
Recruiting
Stonecrest, Georgia, United States, 30038
Contacts
Principal Investigator:
Rabahuddin Syed
GSK Investigational Site
Recruiting
Chicago, Illinois, United States, 60611
Contacts
Principal Investigator:
Daniel Meza
GSK Investigational Site
Recruiting
Baltimore, Maryland, United States, 21224
Contacts
Principal Investigator:
Sarath Raju
GSK Investigational Site
Recruiting
Clarkston, Michigan, United States, 48346
Contacts
Principal Investigator:
Dean Moscovic
GSK Investigational Site
Recruiting
Flint, Michigan, United States, 48504-4730
Contacts
Principal Investigator:
Ahmed Arif
GSK Investigational Site
Recruiting
St Louis, Missouri, United States, 63110
Contacts
Principal Investigator:
Kaharu Sumino
GSK Investigational Site
Recruiting
Henderson, Nevada, United States, 89052-5015
Contacts
Principal Investigator:
Vikas Sayal
GSK Investigational Site
Recruiting
Las Vegas, Nevada, United States, 89123-2874
Contacts
Principal Investigator:
Vrijendra Hoon
GSK Investigational Site
Recruiting
Reno, Nevada, United States, 89502
Contacts
Principal Investigator:
Farah Madhani-Lovely
GSK Investigational Site
Recruiting
North Massapequa, New York, United States, 11758
Contacts
Principal Investigator:
Michael DiGiovanna
GSK Investigational Site
Recruiting
Winston-Salem, North Carolina, United States, 27103
Contacts
Principal Investigator:
Farhan Ahmed
GSK Investigational Site
Recruiting
Winston-Salem, North Carolina, United States, 27104
Contacts
Principal Investigator:
Jessica Bon
GSK Investigational Site
Recruiting
Greenville, South Carolina, United States, 29607
Contacts
Principal Investigator:
Eric Garcia-Torres
GSK Investigational Site
Recruiting
Rock Hill, South Carolina, United States, 29732
Contacts
Principal Investigator:
Michael Denenberg
GSK Investigational Site
Recruiting
Franklin, Tennessee, United States, 37067
Contacts
Principal Investigator:
Aaron Milstone
GSK Investigational Site
Recruiting
Corsicana, Texas, United States, 75110
Contacts
Principal Investigator:
John Updegrove
GSK Investigational Site
Recruiting
Dallas, Texas, United States, 75234
Contacts
Principal Investigator:
Chaitanya Tatineni
GSK Investigational Site
Recruiting
Houston, Texas, United States, 77058-2805
Contacts
Principal Investigator:
Alfred Maksoud
GSK Investigational Site
Recruiting
Houston, Texas, United States, 77084
Contacts
Principal Investigator:
Ajay Jain
GSK Investigational Site
Recruiting
Houston, Texas, United States, 77089
Contacts
Principal Investigator:
Sandeep Gupta
GSK Investigational Site
Recruiting
McKinney, Texas, United States, 75069
Contacts
Principal Investigator:
Shahrukh Kureishy
GSK Investigational Site
Recruiting
Pearland, Texas, United States, 77584
Contacts
Principal Investigator:
Mohammad Siddiqui
GSK Investigational Site
Recruiting
Richmond, British Columbia, Canada, V6V 2L1
Contacts
Principal Investigator:
Alexandra Lucas
GSK Investigational Site
Recruiting
Ajax, Ontario, Canada, L1S 2J5
Contacts
Principal Investigator:
George Philteos
GSK Investigational Site
Recruiting
Toronto, Ontario, Canada, M5T 3A9
Contacts
Principal Investigator:
Kenneth Chapman
GSK Investigational Site
Recruiting
Windsor, Ontario, Canada, N8X 1T3
Contacts
Principal Investigator:
Syed Anees
GSK Investigational Site
Recruiting
Saint-Charles-Borromée, Quebec, Canada, J6E 2B4
Contacts
Principal Investigator:
Bonavuth Pek
GSK Investigational Site
Recruiting
Sherbrooke, Quebec, Canada, J1L 0H8
Contacts
Principal Investigator:
Philippe Lachapelle
GSK Investigational Site
Recruiting
Saskatoon, Saskatchewan, Canada, S7N 0W8
Contacts
Principal Investigator:
Darcy Marciniuk
Sponsor
GlaxoSmithKline
Last update posted
Oct 5, 2026
Last verified
Sep, 2026
Keywords
Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-23. This information was provided to ClinicalTrials.gov by GlaxoSmithKline on 2026-10-05. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.