Recruiting

TEC-S

Sponsor:

Massachusetts General Hospital

Code:

NCT06967545

Conditions

Suicide Attempt

Suicide Ideation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)

Study Details

Brief summary:

This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among adults with recent and frequent suicide ideation.

Conditions

Suicide Attempt

Suicide Ideation

Study ID

NCT06967545

Start date

Jan 20, 2026

Status verified date

Jul, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Oct 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults ages 18+
  • Relatively frequent and recent (≥5 days within the past-month) active suicidal thoughts as assessed via SITBI-R.
  • Willing and able to provide at least one emergency contact (name, phone number, relation).
  • Owns an Android or iOS smartphone.
  • Possesses at least occasional access to Wi-Fi-enabled internet for data down/uploads.
  • Fluent in English and willing to provide informed consent.
  • Living in the Boston metropolitan area (i.e., \~50 mile radius around Boston, MA)

Exclusion Criteria:

  • Recent (past 3-month) hypo/manic symptoms or homicidal ideation or lifetime psychosis spectrum diagnosis as assessed via MINI 7.0.2.
  • Recent acute suicide risk operationalized as affirmative responses to BOTH below items during structured clinical interview AND evaluation by the PI in consultation with Mentors/Advisor Drs. Wilhelm, Kleiman, and/or Bentley:
  • At any time in past week: ≥ 8/10 current intent to act on suicidal thoughts (0 \["not at all"\] to 10 \["extremely strong"\]); AND
  • At any time in past week: thought of a specific suicide plan (i.e, known method/means and/or location) with access to lethal means
  • Impaired vision (e.g., legal blindness), technological illiteracy, or intellectual disability that might impair ability to provide valid data and/or informed consent.

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Smartphone-delivered active Therapeutic Evaluative Conditioning for Suicide (active TEC)

Optional smartphone-delivered active Therapeutic Evaluative Conditioning for Suicide (active TEC-S) for 30 days.

Interventions

Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)

Therapeutic Evaluative Conditioning for Suicide (active TEC-S) is a behavioral treatment where participants are given optional access to a computerized task/game where they repeatedly pair suicidal behavior stimuli (pictures, words) with other negative stimuli and self-related stimuli with positive stimuli.

Primary outcome measure

  • TEC-S Acceptability [ Time Frame: Through completion of treatment phase (day 1 through 30) ]
  • TEC-S Safety [ Time Frame: Through completion of treatment phase (day 1 through 30) ]

Central Contacts and Locations

Central contacts

Adam C Jaroszewski, PhD

781-258-3082ajaroszewski@mgh.harvard.edu

Locations

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Adam Jaroszewski, Ph.D.

617-724-9149ajaroszewski@mgh.harvard.edu

More Information

Sponsor

Massachusetts General Hospital

Last update posted

Jul 10, 2026

Last verified

Jul, 2026

Keywords

  • Suicide
  • Ecological momentary assessment (EMA)
  • Therapeutic Evaluative Conditioning (TEC)

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Massachusetts General Hospital on 2026-07-10.