Recruiting

Neurologic Exam Scale

Sponsor:

University of Wisconsin, Madison

Code:

NCT06981156

Conditions

Pediatric Brain Tumor

Pediatric Spine Tumor

Eligibility Criteria

Sex: All

Age: 1 - 17

Healthy Volunteers: Not accepted

Interventions

pNANO Assessment

Study Details

Brief summary:

This study aims to investigate a neurologic exam scale to provide an objective and more standard way to assess tumor response in pediatric patients with brain and spinal cord tumors.

Conditions

Pediatric Brain Tumor

Pediatric Spine Tumor

Study ID

NCT06981156

Start date

May 13, 2025

Status verified date

Jul, 2026

Completion date

Jan, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 1 - 17

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • greater than or equal to 1 year old
  • must be seen in the pediatric clinic
  • Radiographic or histologic confirmation of a brain or spine tumor at the time of initial diagnosis
  • Patient or parent/guardian must be able to understand the consent and be willing to sign a written informed consent document according to institutional guidelines.

Exclusion Criteria:

  • none specified

Study Design

Enrollment

252 participants

Anticipated

Interventions and Outcome Measures

Arms

Pediatric Brain and Spine Tumor Patients

Interventions

pNANO Assessment

pNANO assesses patient gait, strength, cerebellar function, visual fields, visual acuity, facial strength, level of consciousness, extraocular movement, dysarthria, and dysphagia

The patient will be assessed by 2-3 different clinicians during each of 2 visits.

Primary outcome measure

  • Inter-observer Variability in pNANO Scores: Difference in Mean Cumulative Scores [ Time Frame: Visit 1 (baseline), Visit 2 (up to 6 months) ]

Central Contacts and Locations

Central contacts

Cancer Connect

800-622-8922clinicaltrials@cancer.wisc.edu

Locations

American Family Children's Hospital

Recruiting

Madison, Wisconsin, United States, 53792

More Information

Sponsor

University of Wisconsin, Madison

Last update posted

Jul 21, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-25. This information was provided to ClinicalTrials.gov by University of Wisconsin, Madison on 2026-07-21. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.