Recruiting

Mindfulness Based Relapse Prevention

Sponsor:

University of New Mexico

Code:

NCT06982443

Conditions

Alcohol Use

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Mindfulness based relapse prevention

Study Details

Brief summary:

The goal of this clinical trial is to examine the effects of mindfulness based relapse prevention on self-regulation overtime and drinking in daily life through the use of wearable heart rate sensors during mindfulness groups and answering assessment questions 3 times per day during the course of treatment. The main questions that it aims to answer are:

1. What changes in self-regulation as measured through heart rate variability are observed during a mindfulness intervention and how do those self-regulatory changes affect drinking after treatment?
2. How do changes in heart rate variability affect drinking, craving, and negative affectivity in daily life?

Participants will:

1. Answer questions related to their mood and drinking behaviors.
2. Wear their sensors during an 8-week treatment period with 1 group per week.
3. Answer questions 3 times a day during the treatment period. 4.) Return their sensors via a pre-stamped package and answer questions about their mood and drinking behaviors 3- and 6-months after the mindfulness groups end.

Conditions

Alcohol Use

Study ID

NCT06982443

Start date

Oct 1, 2025

Status verified date

Jul, 2026

Completion date

Sep 1, 2029

Anticipated

Primary completion date

Mar 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. 18 years of age or older
2. Meet criteria for a moderate to severe alcohol use disorder within the previous 3-months.
3. Able to attend group meetings at the time listed on the recruitment materials.
4. Willing to wear a sensor for the 8-week intervention period and return the sensor after the immediate follow-up.
5. Have a phone/tablet/computer with internet access.
6. Be able to comprehend and consent to study requirements in English.
7. Have access to a valid U.S. mailing address for receiving the HRV sensors and reside in the United States.

Exclusion Criteria:

1. Current symptoms of psychosis or mania.
2. Have a substance use disorder requiring a higher level of care than outpatient treatment (e.g., severe alcohol use disorder requiring inpatient detoxification).
3. Have a history of pulmonary or cardiovascular disease that interferes with sensor data collection and HRV metrics (i.e., ectopic beats, arrythmia, congenital heart disease).

Study Design

Enrollment

120 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: MBRP

Interventions

Mindfulness based relapse prevention

Mindfulness-based relapse prevention (MBRP) is a group-based treatment to provide individuals with skills intended to foster increased awareness of triggers, destructive habitual patterns, and "automatic" reactions to triggering experiences. Mindfulness practices in MBRP are designed to help individuals pause, observe present experience, and bring awareness to the range of choices available in every moment. Through MBRP individuals learn to respond in ways that serve them, rather than react in ways that are detrimental to their health and happiness.

Primary outcome measure

  • Recovery from AUD [ Time Frame: Change from baseline to 6-month follow-up ]
  • Psychophysiological self-regulation [ Time Frame: Change from baseline to immediate follow-up ]
  • Addiction Cycle Domains in Daily Life [ Time Frame: Measured 3x daily ]

Central Contacts and Locations

Locations

University of New Mexico

Recruiting

Albuquerque, New Mexico, United States, 87131

Contacts

Matison W McCool, PhD

505-228-0142mwmccool@unm.edu

More Information

Sponsor

University of New Mexico

Last update posted

Jul 15, 2026

Last verified

Jul, 2026

Keywords

  • alcohol
  • mindfulness
  • harm reduction

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of New Mexico on 2026-07-15.