Recruiting

Practical Geriatric Assessment

Sponsor:

Brigham and Women's Hospital

Code:

NCT06987890

Conditions

Lung Cancer (NSCLC)

Geriatric Assessment

Stereotactic Body Radiation Therapy (SBRT)

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Not accepted

Interventions

Practical Geriatric Assessment

Study Details

Brief summary:

National guidelines recommend that older adults with cancer undergo a special health assessment before starting cancer treatment. This type of assessment evaluates physical function, nutrition, social support, psychological well-being, medical conditions (both cancer-related and non-cancer-related), and cognitive function. The results can help doctors make better treatment decisions and determine whether additional support services-such as nutrition counseling, physical therapy, or social work-would be beneficial. Even though these assessments are recommended, they are not typically used because they need to be performed by a specialist and can take over an hour to complete. Given these challenges, a 10-15-minute assessment called the Practical Geriatric Assessment (PGA) was recently developed. The PGA can be completed by any healthcare provider and helps identify older adults who may need extra support alongside their cancer treatment. While the PGA has the potential to make geriatric assessments more accessible, the investigators do not yet know whether patients will find it useful or easy to complete.

Additionally, it is unclear whether using the PGA will lead to more referrals for recommended supportive care services. This study aims to address these questions. The investigators will evaluate whether using the PGA impacts the number of patients referred to recommended supportive care services. Investigators will also evaluate how participants feel about completing the PGA, including how easy or difficult it is, and to assess the feasibility of implementing this survey on a larger scale. Finally, the investigators will use facial photographs and audio-visual data from the PGA to develop and evaluate artificial intelligence algorithm(s) to identify vulnerable patients who might benefit from additional supportive care services; namely, FaceAge, a validated deep learning model capable of estimating biological age from still facial images.

Conditions

Lung Cancer (NSCLC)

Geriatric Assessment

Stereotactic Body Radiation Therapy (SBRT)

Study ID

NCT06987890

Start date

May 26, 2025

Status verified date

Jun, 2026

Completion date

Dec 26, 2026

Anticipated

Primary completion date

Dec 26, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 65+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 65 years old at time of study enrollment.
  • Radiographically or pathologically confirmed stage I-II non-small cell lung cancer.
  • All patients must have undergone appropriate complete imaging of their cancer consistent with the standard of care.
  • Patient is expected to undergo stereotactic body radiation therapy (SBRT)
  • Able to read questions in English or willing to complete survey questionnaires with the assistance of an interpreter.

Exclusion Criteria:

  • There are no exclusion criteria.

Study Design

Enrollment

64 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: PGA IMPLEMENTED IN NSCLC WITH SBRT

Providers will be made aware of PGA results and all recommended referrals based on PGA results. Providers will be reminded weekly for up to one month regarding these recommendations.

no intervention: SUPPORTIVE CARE WITHOUT PGA IN NSCLC WITH SBRT

Though PGA questions will be completed to characterize baseline impairment, providers will not be notified of PGA results or recommended referrals based on PGA results. Providers will assess for geriatric impairment at their discretion, and will make any service referrals they deem necessary, also at their discretion.

Interventions

Practical Geriatric Assessment

The Practical Geriatric Assessment (PGA) is an abridged version of the Comprehensive Geriatric Assessment (CGA). This tool can be completed by any provider within 10-25 minutes while still capturing the key domains of the CGA. This screening tool, which is now recommended by American Society of Clinical Oncology (ASCO), the International Society for Geriatric Oncology (SIOG), and the Cancer \& Aging Research Group (CARG), has the potential capacity to delineate relevant baseline features in geriatric populations without creating undue provider burden.

Primary outcome measure

  • Rate of referral to recommended supportive care services [ Time Frame: One-month post PGA Implementation ]

Central Contacts and Locations

Locations

Brigham and Women's Hospital

Recruiting

Boston, Massachusetts, United States, 02115

Contacts

More Information

Sponsor

Brigham and Women's Hospital

Last update posted

Aug 25, 2026

Last verified

Jun, 2026

Keywords

  • Lung Cancer
  • Geriatric

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Brigham and Women's Hospital on 2026-08-25.