Recruiting

Inhaled & Intravenous Anesthesia

Sponsor:

University of Kansas Medical Center

Code:

NCT07001267

Conditions

Acute Ischemic Stroke Patients

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Anesthesia drugs during the surgery

Study Details

Brief summary:

This study is being done to compare outcomes after surgery for individuals who receive anesthesia through by inhaling medication and individuals who receive anesthesia intravenously by needle when experiencing treatment for their stroke. Currently very little is known about the outcomes for patients when comparing these two techniques of providing anesthesia during surgery. This study will provide information regarding outcomes that will help health care providers decide which technique will be better for patients

Conditions

Acute Ischemic Stroke Patients

Study ID

NCT07001267

Start date

Jun 4, 2025

Status verified date

Mar, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

May 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • >18 years Acute ischemic stroke requiring endovascular treatment.

Exclusion Criteria:

  • <18 years
  • Pregnant patients
  • Patients with malignant hyperthermia
  • Allergies or any contraindications to either inhalational or intravenous agents
  • Patients already on intravenous anesthetic infusions
  • Prisoners
  • Students and employees

Study Design

Enrollment

120 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: inhalational sevoflurane

When treated for acute ischemic stroke, patient will receive inhalation sevoflurane as anesthesia

active comparator: intravenous propofol infusion

When treated for acute ischemic stroke, patient will receive intravenous propofol infusion as anesthesia

Interventions

Anesthesia drugs during the surgery

During treatment for acute ischemic stroke, patients will be given either inhalation or intravenous anesthesia.

Primary outcome measure

  • Functional Independence at 90 days [ Time Frame: From enrollment to 90 days after treatment ]

Central Contacts and Locations

Central contacts

Arun George, MD

913-588-6670ageorge9@kumc.edu

Locations

University of Kansas Medical Center

Recruiting

Kansas City, Kansas, United States, 66160

Contacts

Arun George, MD

913-588-6670ageorge9@kumc.edu

More Information

Sponsor

University of Kansas Medical Center

Last update posted

Mar 12, 2026

Last verified

Mar, 2026

Keywords

  • Inhalation anesthesia
  • Intravenous anesthesia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Kansas Medical Center on 2026-03-12.