Recruiting

hCG

Sponsor:

Fertility Center of Las Vegas

Code:

NCT07004192

Conditions

Infertility (IVF Patients)

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Interventions

HCG injection

No intervention

Study Details

Brief summary:

This prospective randomized trial will assess the relevance, if any, of a corpus luteum induced by hCG in transfers of thawed embryos.

Conditions

Infertility (IVF Patients)

Study ID

NCT07004192

Start date

Jun 2, 2025

Status verified date

Jun, 2025

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Female adult expecting to receive transfer of a thawed embryo.
2. At least one available frozen blastocyst of transferrable quality.
3. Non-menopausal female with at least one antral follicle.
4. Use of pre-implantation genetic testing (PGT), embryos derived from donor oocytes and/or donor sperm, a gestational carrier, and history of prior transfer(s) regardless of outcome are allowed.
5. Subsequent embryo transfers after failed transfers under this study are allowed, but not after a transfer that has resulted in ongoing pregnancy at ten weeks gestation under this study.

Exclusion Criteria:

1. Minors (age<18 years).
2. Use of embryo(s) frozen at another center.
3. Patient insistent on transfer of two embryos.
4. Patient or partner unable to provide informed consent in English.
5. Patient already enrolled in any other research study for her embryo transfer.
6. History of anti-phospholipid syndrome or any other indication for use of Lovenox in pregnancy.
7. Patient for whom the physician assesses this protocol is inappropriate or unsafe.

Study Design

Enrollment

220 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: hCG Group

This group receives one injection of hCG.

active comparator: No hCG Group

This arm receives no hCG.

Interventions

HCG injection

5000 IU hCG injection

No intervention

No hCG administered in this group.

Primary outcome measure

  • Blood pressure [ Time Frame: Third trimester of pregnancy ]

Central Contacts and Locations

Central contacts

Locations

Fertility Center of Las Vegas

Recruiting

Las Vegas, Nevada, United States, 89113

Contacts

More Information

Sponsor

Fertility Center of Las Vegas

Last update posted

Jul 1, 2025

Last verified

Jun, 2025

Keywords

  • Thawed embryo transfer

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Fertility Center of Las Vegas on 2025-07-01.