Recruiting

AI Assisted Intervention

Sponsor:

Mayo Clinic

Code:

NCT07009210

Conditions

Serious Illness

Existential Distress

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AI Assisted Personalized Legacy Program

Study Details

Brief summary:

The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the AI Assisted Personalized Legacy Program intervention to patients with serious illness.

Conditions

Serious Illness

Existential Distress

Study ID

NCT07009210

Start date

Aug 11, 2025

Status verified date

Jun, 2026

Completion date

Jun 30, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Participant population: Adults with serious illness - defined as a health condition that carries a high risk of mortality

Inclusion Criteria for patients:

1. Age ≥18 years
2. English fluency
3. Provide informed consent
4. Ability to complete questionnaire(s) by themselves or with assistance

Exclusion Criteria:

1. Other psychological co-morbidities such as untreated schizophrenia, bipolar disease
2. Recent suicide attempt or psychiatric illness severe enough that hospitalization has been necessary in last 6 months
3. Active delirium
4. Advanced dementia
5. Participation in concurrent legacy offerings through the palliative care clinic

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: AI Assisted Personalized Legacy Program

Interventions

AI Assisted Personalized Legacy Program

AI Assisted Personalized Legacy Program will be facilitated by a clinician trained in legacy work.

Primary outcome measure

  • Feasibility Number [ Time Frame: 2 years ]
  • Acceptability [ Time Frame: 5-10 days post-delivery of the final legacy document ]

Central Contacts and Locations

Central contacts

Locations

Mayo Clinic

Recruiting

Phoenix, Arizona, United States, 85054

Contacts

Principal Investigator:

Mark K. Edwin, MD

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

More Information

Sponsor

Mayo Clinic

Last update posted

Jun 17, 2026

Last verified

Jun, 2026

Keywords

  • Legacy Work

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-06-17.