Recruiting

Progressive Muscle Relaxation & Walking

Sponsor:

University of Illinois at Chicago

Code:

NCT07014111

Conditions

End Stage Renal Disease on Dialysis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Fight Fatigue

Attention Control

Study Details

Brief summary:

Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.

Conditions

End Stage Renal Disease on Dialysis

Study ID

NCT07014111

Start date

Sep 2, 2025

Status verified date

Aug, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Feb, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosis of ESKD diagnosis and receiving hemodialysis for at least 3 months
  • Can read and speak English
  • Fatigue measured via visual analogue scale, score ≥4 over the last week
  • Able to stand and walk one block
  • Has a cell phone that can receive text messages

Exclusion Criteria:

  • Patient's nephrologist refuses for them to participate
  • Unstable angina
  • Unstable pulmonary disease or pulmonary symptoms that preclude participation
  • Lower-extremity amputation without prosthetic (BKA, AKA) -Orthopedic or neurologic condition that would preclude walking or tensing/releasing of muscles-
  • Cognitive impairment that, in the judgement of the research team, precludes trial participation
  • Participation in the formative phase of the development of Fight Fatigue

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Fight Fatigue

Combined progressive muscle relaxation and walking (increasing step count) 12-week intervention that consists of education/training followed by text messages

active comparator: Attention Control

End-stage kidney disease education, followed by text messages (over 12 weeks)

Interventions

Fight Fatigue

Combined progressive muscle relaxation and walking (increasing step count) 12-week intervention that consists of education/training followed by text messages.

Attention Control

End-stage kidney disease education

Primary outcome measure

  • Feasibility of recruitment [ Time Frame: Baseline to week 12 ]
  • Feasibility of retention [ Time Frame: Baseline to week 12 ]
  • Acceptability [ Time Frame: End of study (Week 12) ]
  • Adherence to the study protocol [ Time Frame: Baseline to week 12 ]

Central Contacts and Locations

Central contacts

Mary Hannan, PhD

3123554838mhanna22@uic.edu

Locations

UI Health/University of Illinois Chicago

Recruiting

Chicago, Illinois, United States, 60612

Contacts

Mary Hannan

312-355-4838mhanna22@uic.edu

More Information

Sponsor

University of Illinois at Chicago

Last update posted

Sep 2, 2026

Last verified

Aug, 2026

Keywords

  • Fatigue

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Illinois at Chicago on 2026-09-02.