Recruiting

PRP

Sponsor:

Generation Next Fertility

Code:

NCT07020546

Conditions

Infertility

Poor Ovarian Reserve

Embryo Growth Disorder

in Vitro Fertilization

Eligibility Criteria

Sex: Female

Age: 18 - 47

Healthy Volunteers: Accepted

Interventions

Ovarian Platelet-rich plasma (PRP) injections

Study Details

Brief summary:

Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.

Conditions

Infertility

Poor Ovarian Reserve

Embryo Growth Disorder

in Vitro Fertilization

Study ID

NCT07020546

Start date

Jul 8, 2025

Status verified date

Jun, 2025

Completion date

Aug 30, 2026

Anticipated

Primary completion date

Jun 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 47

Healthy Volunteers: Accepted

Inclusion Criteria:

  • No none contraindications to IVF or PRP treatment
  • Adequate ovarian reserves and AMH level
  • Willingness to undergo two IVF cycles and oPRP treatment

Exclusion Criteria:

  • Anovulation due to menopause or perimenopause
  • Any health conditions that are contraindicated for IVF or oPRP treatment

Study Design

Enrollment

180 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Embryo Development Before and After Ovarian PRP Using Time-Lapse AI Embryo Quality Score

Patients will undergo two IVF cycles. The first cycle will be before ovarian PRP treatment and the second will be after. The embryo development measured by data gathered in time-lapse imaging and AI software will be used to determine differences between the groups within the same patient

Interventions

Ovarian Platelet-rich plasma (PRP) injections

This is a procedure that our patients receive at our clinic. We want to use the AI software to evaluate embryo development before and after treatment to see if there is a difference in embryo quality after PRP treatment within the same patient.

Primary outcome measure

  • Blastocyst formation and embryo quality [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Alicia L Broussard, PhD

3174456958a.broussard@generationnextfertility.com

Jesse Hade, MD

2126410906j.hade@generationnextfertility.com

Locations

Generation Next Fertility

Recruiting

New York, New York, United States, 10022

Contacts

Alicia L Broussard, PhD

212-641-0906a.broussard@generationnextfertility.com

More Information

Sponsor

Generation Next Fertility

Last update posted

Jul 9, 2025

Last verified

Jun, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-10. This information was provided to ClinicalTrials.gov by Generation Next Fertility on 2025-07-09. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.