Recruiting

Remote Symptom Monitoring

Sponsor:

University of Calgary

Code:

NCT07024329

Conditions

Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Remote Symptom Monitoring and Management

Clinic Team Huddle

Study Details

Brief summary:

The goal of this study is to understand if the implementation of a remote symptom monitoring and management program improves outcomes. The program will provide patients the opportunity to complete electronic Patient Reported Outcomes (PROs) questionnaires from home between appointments and receive tailored advice from a study nurse. A second goal of this study is to examine the impact of electronic symptom monitoring on clinic efficiencies.

The main question it aims to answer is:

• What impact does implementing digitally enabled remote symptom monitoring and management (RESPONd) between ambulatory oncology visits have on patient outcomes and system efficiencies?

Participants will:

  • Report their symptoms and concerns from home by completing the electronic symptom monitoring questionnaire.
  • Discuss their symptoms and concerns with a study nurse.
  • Provide feedback about their experience at important timepoints during the study.
  • Participate as usual in ambulatory clinic appointments.

Conditions

Cancer

Study ID

NCT07024329

Start date

May 16, 2025

Status verified date

Apr, 2026

Completion date

Mar 31, 2027

Anticipated

Primary completion date

Nov 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18
  • Have cancer
  • Receiving care in one of the participating clinics.
  • Able to sign up for MyAHS Connect and consent.
  • Have access to a digital device at home
  • Able to complete their electronic PROs questionnaire without support from the clinic team on a weekly (patients on active treatment) or monthly (patients on follow-up) basis, for the duration of the intervention or until they are discharged from the clinic.
  • Regular access to a telephone in order for the study nurse to call patients to provide symptom management support.

Exclusion Criteria:

  • Patients with cognitive disabilities or who cannot reliably report symptoms independently.
  • Patients not residing in Alberta, as government-issued ID is required to register for MyAHS Connect.
  • Patients who do not have regular access to a telephone, as the study nurse needs to be able to call patients to provide symptom management support.
  • Patients who do not speak English, or who do not have an English-speaking friend, family member, or caregiver to assist them, as the electronic PROs questionnaire is only available in English at this time.

Study Design

Enrollment

1055 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: RESPONd

Participants will be recruited and supported to complete electronic PROs questionnaires. Study nurses will monitor the electronic PROs completed between clinic visits and contact patients to provide personalized support.

no intervention: Non-RESPONd

Usual care.

Interventions

Remote Symptom Monitoring and Management

A study nurse will digitally monitor symptom complexity and provide symptom management between clinic visits. This will increase the frequency of collection and use of electronic PROs to provide responsive symptom management. Electronic PROs are collected digitally, and a complexity algorithm is used to flag patients with high symptom complexity. This will allow the study nurse to proactively manage symptoms in a timelier way.

Clinic Team Huddle

Support will be provided to clinic teams to implement a team huddle (team planning session) one week prior to clinics, to assess how additional electronic PROs data for patients participating in RESPONd impacts their ability to identify stable patients with low symptom complexity who could receive virtual care or Registered Nurse (RN) led clinic care.

Primary outcome measure

  • Quality of Life (QoL) [ Time Frame: Baseline, 3 months and 6 months ]
  • Self-rated health [ Time Frame: Baseline, 3 months and 6 months ]
  • Rate of Emergency department (ED) visits [ Time Frame: Baseline through study completion, an average of 18 months ]
  • Rate of Hospital admissions [ Time Frame: Baseline through study completion, an average of 18 months ]
  • Economic outcome measure - Incremental cost-effectiveness ratio (ICER) [ Time Frame: Baseline through study completion, an average of 18 months ]
  • Economic outcome measures - Quality adjusted life years (QUALYs) [ Time Frame: Baseline through study completion, an average of 18 months ]

Central Contacts and Locations

Central contacts

Chizoba Anyimukwu, MPH, DrPH

587-943-3556chizoba.anyimukwu@albertahealthservices.ca

Benedicta Asante, RSW, MSW

587-943-3562benedicta.asante@albertahealthservices.ca

Locations

Arthur J. E. Child Comprehensive Cancer Centre

Recruiting

Calgary, Alberta, Canada, T2N 4N1

Contacts

Chizoba Anyimukwu

587-943-3556chizoba.anyimukwu@ahs.ca

Cross Cancer Institute

Recruiting

Edmonton, Alberta, Canada, T6G 1Z2

Contacts

Chizoba Anyimukwu

587-943-3556chizoba.anyimukwu@ahs.ca

Central Alberta Cancer Centre

Recruiting

Red Deer, Alberta, Canada, T4N 6R2

Contacts

Chizoba Anyimukwu

587-943-3556chizoba.anyimukwu@ahs.ca

More Information

Sponsor

University of Calgary

Last update posted

Apr 30, 2026

Last verified

Apr, 2026

Keywords

  • Patient Reported Outcomes
  • Quality of Life
  • Clinical Decision Making
  • Patient Reported Outcome Measures
  • Patient Experience
  • Health Service Utilization
  • Symptom Management
  • PROMs
  • PROs

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Calgary on 2026-04-30.