Recruiting

Pre-Workout Supplement

Sponsor:

St. Louis University

Code:

NCT07024940

Conditions

Coffee

Anthocyanins

Exercise Performance

Eligibility Criteria

Sex: All

Age: 18 - 35

Healthy Volunteers: Accepted

Interventions

Ethiopian Coffee

Supplement

Water (Placebo)

Study Details

Brief summary:

The investigators are conducting a study to see how a commercial pre-workout supplement, coffee, and water affect how well people perform. The study is conducted across four visits. The first visit is to assess the participants, and the next three visits are for testing. Each participant will drink a randomly assigned beverage 45 minutes before testing. Throughout the study, the participants will complete three testing days-each at least three days apart-so they can try all three drinks. The first test is the Wingate test, where the participants pedal as fast as they can for 30 seconds against a set resistance. The second test is a 1-mile treadmill run/walk on an incline, where the participant tries to complete the distance as fast as possible. The third test measures reaction time using light-up buttons to see how quickly a participant responds by touching them. These tests will help determine if any of the drinks improve performance. The results can help people choose the best drink for their workouts or races.

Conditions

Coffee

Anthocyanins

Exercise Performance

Study ID

NCT07024940

Start date

Apr 25, 2025

Status verified date

Jun, 2025

Completion date

Sep 1, 2026

Anticipated

Primary completion date

Aug 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 35

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Are a healthy male or female adult aged 18-35 years old
  • Regularly engaged in resistance training or aerobic exercise at least 3 times per week, at least 30 minutes a week for the past 6 months
  • Able to provide written informed consent

Exclusion Criteria:

  • Have a history of or currently have a cardiovascular or metabolic disease (e.g., diabetes, prediabetes, hypertension, arrhythmia, heart attack, stroke, non-alcoholic fatty liver disease, chronic kidney disease)
  • History of seizure disorder
  • Currently taking prescription medications (e.g., beta-blockers, antidepressants, anti-anxiety, pain killers)
  • Currently pregnant, breastfeeding, pregnant within the past year, or a chance of being pregnant
  • Recent participation in another clinical trial
  • Any sensitivities to caffeine, coffee, berries, maltodextrin, monk fruit extract, or any known food allergies
  • Currently undertaking serious exercise training (6 or more days of the week)
  • Recently started taking creatine or beta-alanine daily within the past 3 months. (If greater than 3 months taken consistently is okay)

Study Design

Enrollment

12 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Ethiopian Coffee

A light roast Ethiopian Coffee is used based on previous research using the same technique for brewing. The coffee is brewed using the Aeropress coffee maker and the Timemore C3Pro hand grinder to grind the coffee. The recipe uses 15 grams of ground coffee set at the same grind setting (16 clicks) and 200 grams of water to have a target cup size of 175 mL plus 50 grams of ice to rapidly cool down the drink for consumption.

experimental: Anthocyanin-Caffeine

An anthocyanin-caffeine pre-workout supplement containing 120 mg of anthocyanins from New Zealand Blackcurrant berries, along with 120 mg of caffeine. This single-serve packet is stirred into 8 ounces of water and served.

placebo comparator: Water

Water used as a constant water intake across all three arms

Interventions

Ethiopian Coffee

Ethiopian Coffee is used as a real-world example of one of the most common drinks in the world.

Supplement

A pre-workout supplement that contains anthocyanins and caffeine as ergogenic aids

Water (Placebo)

Bottled water acting as the placebo

Primary outcome measure

  • Change in anaerobic power measured by a 30-second all-out effort on a cycle ergometer [ Time Frame: At 45 minutes post-dose for each intervention condition ]

Central Contacts and Locations

Central contacts

Dylan Moffatt, Bsc

314-977-8675dylan.moffatt@slu.edu

Locations

Saint Louis University

Recruiting

St Louis, Missouri, United States, 63103

Contacts

Hossein Rafiei, PhD

314-977-8675hossein.rafiei@health.slu.edu

More Information

Sponsor

St. Louis University

Last update posted

Aug 19, 2025

Last verified

Jun, 2025

Keywords

  • Coffee
  • Caffeine
  • Wingate
  • Anthocyanin-Caffeine
  • 1-mile
  • VO2 max
  • pre-workout
  • supplement

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by St. Louis University on 2025-08-19.