Recruiting

Bed PositioningThe ARISE Study - Use of Vertical Positioning

Sponsor:

University of Alabama at Birmingham

Code:

NCT07025421

Conditions

Acute Respiratory Distress Syndrome

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Intervention Upright Bed positioning

Study Details

Brief summary:

The pilot study will randomize 40 ARDS patients who if proning were required would be randomized to upright bed positioning or to stand of care with bed in the head of bed elevation position

Conditions

Acute Respiratory Distress Syndrome

Study ID

NCT07025421

Start date

Aug 25, 2025

Status verified date

Aug, 2026

Completion date

Aug 31, 2028

Anticipated

Primary completion date

Jun 30, 2028

Anticipated

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

\- Acute Respiratory Distress Syndrome

Exclusion Criteria:

Cancer
Active tracheostomy

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Intervention

Upright bed positioning

no intervention: Standard of Care

Standard of Care Head of Bed Elevation

Interventions

Intervention Upright Bed positioning

Patient in receipt of the upright bed positioning will receive daily upright bed positioning time each day of mechanical ventilation following the time required by institutional protocol for ARDS - associated prone positioning

Primary outcome measure

Change in Tidal Volume [ Time Frame: within first 7 days of mechanical ventilation ]

Central Contacts and Locations

Central contacts

peter morris, md

205-934-5548 pmorris@uabmc.edu

Locations

University of Alabama at Birmingham

Recruiting

Birmingham, Alabama, United States, 35223

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Aug 27, 2026

Last verified

Aug, 2026

Keywords

Bed Position

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2026-08-27.