Recruiting

Semiconductor Socks

Sponsor:

University of Colorado, Denver

Code:

NCT07025733

Conditions

Ankle Sprain

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Interventions

Semiconductor Embedded Sock

Control Compression Sock

Study Details

Brief summary:

The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains. The main questions it aims to answer are:

1. How does semiconductor embedded sock effect outcomes in patients undergoing rehabilitation from ankle injury?
2. How does semiconductor embedded socks effect injury symptoms and function throughout the course of treatment?

Researchers will compare semiconductor embedded socks with typical compression socks to determine differences in healing.

Participants will be given the socks and be asked to wear them throughout the healing process and record symptoms and functional measures.

Conditions

Ankle Sprain

Study ID

NCT07025733

Start date

Apr 10, 2025

Status verified date

Jun, 2025

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Ankle sprain, avulsion fracture, distal fibular fracture
  • Pain for at least 1 day
  • Patients 18-69 years old

Exclusion Criteria:

  • Patients with neurological conditions
  • Patients with prior surgical treatment of lower limb injury
  • Patients with chronic pain conditions
  • Patient with auto-immune or auto-inflammatory disease
  • Patients with tobacco use in last 90 days
  • Patients with history of metabolic disorders
  • Patients with open wound at area of application
  • Patients with acute or systemic infection

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Semiconductor Embedded Sock

placebo comparator: Control Compression Sock

Interventions

Semiconductor Embedded Sock

Semiconductor Embedded sock will be given to this intervention arm

Control Compression Sock

Control sock that is just compression sock

Primary outcome measure

  • FAOS Score [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Study Coordinator

3037243185fahim.choudhury@cuanschutz.edu

Locations

University of Colorado

Recruiting

Aurora, Colorado, United States, 80045

Contacts

Study Coordinator

3037243185nicholas.piccaro@cuanschutz.edu

More Information

Sponsor

University of Colorado, Denver

Last update posted

May 1, 2026

Last verified

Jun, 2025

Keywords

  • ankle sprain
  • ligamentous sprain
  • avulsion fracture
  • distal fibula fracture

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Colorado, Denver on 2026-05-01.