Recruiting

Observational Study

Sponsor:

University of Virginia

Code:

NCT07036315

Conditions

The Focus of the Study is Healthy Volunteers

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

Music intervention

Study Details

Brief summary:

The overall goal of this project is to examine the impact of music's meaning on pain. Relationships between trait affect, meaning in life, and subjective qualities of meaningful music will be assessed. We will also conduct interviews with a subset of participants to determine which aspects of music are most meaningful and how this meaning increases or decreases pain sensations.

Conditions

The Focus of the Study is Healthy Volunteers

Study ID

NCT07036315

Start date

Oct 25, 2025

Status verified date

Nov, 2025

Completion date

Aug 15, 2026

Anticipated

Primary completion date

Jun 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 18-65 years old
  • Absence of acute or chronic pain
  • Normal hearing (either naturally or with assistance of hearing device)
  • Must be able to wear an EEG
  • Able to sign consent

Exclusion Criteria:

  • < 18 or > 65 years old
  • Presence of acute pain (brief pain inventory score > 3)
  • Pregnant women
  • Participant reports that they experience pain on more days than not in the past 6 months (i.e., chronic

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Pain-Modulation

Participants will be exposed to different music clips.

Interventions

Music intervention

Participants will be asked to select different music clips based on meaning, enjoyment and preference.

Primary outcome measure

  • Pain Unpleasantness [ Time Frame: Baseline/Pre-intervention and During the Intervention ]
  • Pain Intensity [ Time Frame: Baseline/Pre-intervention and During the Intervention ]

Central Contacts and Locations

Central contacts

Claudia Denoue, MD

4342436744TTC8WZ@uvahealth.org

Locations

University of Virginia

Recruiting

Charlottesville, Virginia, United States, 22903

Contacts

Patrick Finan, Ph.D.

4349249514finanlab@virginia.edu

Principal Investigator:

Patrick Finan, Ph.D.

More Information

Sponsor

University of Virginia

Last update posted

Nov 25, 2025

Last verified

Nov, 2025

Keywords

  • Music
  • Pain
  • Meaning

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Virginia on 2025-11-25.