Recruiting

Smokefree Family Living

Sponsor:

UCLA

Code:

NCT07049757

Conditions

Tobacco-Related Carcinoma

Smoking Cessation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Smoking cessation education

Survey Administration

Telephone-Based Intervention

Urine Specimen Collection

Silicone Wrist Band

Study Details

Brief summary:

This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the smoke has cleared (third-hand smoke (THS)) among Chinese American smokers and their non-smoking household members. Smoking remains high among Chinese American males with limited ability to speak English. This causes the non-smoking household members to be exposed to THS, which contains many of the same harmful components as smoking and becomes more toxic as it ages. SFL is tailored for Chinese Americans and combines the contents of the Quit Smoking for a Healthy Family (QS) intervention with additional THS education and cleaning strategies. QS focuses on smoking cessation through educational sessions and support. THS education and cleaning strategies provide information on THS and how to clean the home for THS. SFL may help Chinese American smokers and their non-smoking household members learn about the importance of quitting and the dangers of THS, this may improve smoking cessation and reduce THS exposure

Conditions

Tobacco-Related Carcinoma

Smoking Cessation

Study ID

NCT07049757

Start date

Mar 23, 2026

Status verified date

May, 2026

Completion date

Sep 30, 2028

Anticipated

Primary completion date

Mar 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

All Participants (Lay Health Workers, Smokers, Family Participants, and Post-Trial Household Member Group Interview Participants):

1. Must be 18 years of age or older.
2. Must self-identify as Chinese or of Chinese descent (ethnic or cultural identification, not national origin).
3. Must be able to understand in spoken Chinese (Cantonese and/or Mandarin) or English.
4. Able to attend educational sessions in person or via video conferencing.
5. Ability to understand and the willingness to sign a written informed consent document.
6. Have a mobile phone that can receive Short Message Service (SMS) text messages, or an email address and a phone number where they can be reached by the study team.

Lay Health Workers:

1. Must have experience or interest in community outreach and education.
2. Must demonstrate proficiency in language (Cantonese and/or Mandarin or English) sufficient to deliver study materials and interact with participants.
3. Must be affiliated with the Chinese Community Health Resource Center (CCHRC) or recruited through community networks.
4. Must agree to participate in training and intervention delivery activities as outlined in the study protocol.

Smokers (Participants who are current smokers):

1. Must have smoked within the past 30 days, either daily or occasionally.
2. Must have a non-smoking household member.

Family Participants (Non-smoking family/household members):

1. Must live in the same household as the smoker participant.
2. Must not have used any tobacco products in the past 30 days.

Post-Trial Household Member Group Interview Participants:

1\. Living in the same household with the smoker-household member dyad participant being interviewed or considered as a household member.

Exclusion Criteria:

Lay Health Workers, Smokers (Participants who are current smokers) and Family Participants (Non-smoking Family/household members):

1. Currently participating in another smoking cessation program.
2. Non-residents of California.
3. Participants unwilling to provide follow-up contact for assessments at 6 and 12 months.

Lay Health Workers:

1. Lack of willingness or ability to complete training or deliver intervention sessions as required by the study protocol.
2. Inability to maintain confidentiality and professionalism during interactions with study participants.
3. Active participation in conflicting research studies or programs.

Study Design

Enrollment

760 participants

Anticipated

Allocation

Randomized

Intervention Model

Sequential

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Intervention Development (Focus group + Interview)

To achieve information gathering and preliminary adaptation design to prepare for the randomized clinical trial, focus groups and individual interviews with 24 participants (6 Chinese current smokers; 6 former smokers who have stopped smoking within the past 2 years; and 12 family/household members living with a current/former smoker) to review the newly developed or updated intervention materials. The Community Advisory Board (CAB) will also be involved in providing input.

active comparator: Arm I: Quit Smoking for a Healthy Family Group (QS)

Participants attend two QS educational sessions over 45-60 minutes one month apart and receive two follow-up phone calls over 15-30 minutes 1-2 weeks after each session over 6 weeks. Participants also receive a Healthy Family Action Plan as well as a smoking cessation resource guide and set goals on study. Participants then receive THS education and cleaning strategies at 6 months after the initial QS curriculum. Additionally, participants undergo urine sample collection throughout the study and non-smoking family/household members will wear a silicone wristband for 2 days at each assessment.

experimental: Arm II: Smokefree Family Living Group (SFL)

Participants attend two QS educational sessions over 45-60 minutes one month apart and receive two follow-up phone calls over 15-30 minutes 1-2 weeks after each session over 6 weeks. During the second QS educational session, participants receive THS education and cleaning strategies. Participants also receive a Healthy Family Action Plan as well as a smoking cessation resource guide and set goals on study. Additionally, participants undergo urine sample collection throughout the study and non-smoking family/household members will wear a silicone wristband for 2 days at each assessment.

Interventions

Smoking cessation education

Quit Smoking for a Healthy Family (QS) and Smokefree Family Living (SFL) education sessions to promote smoking cessation and reduce tobacco smoke exposure.

Survey Administration

Administered for ancillary studies

Telephone-Based Intervention

Participants will receive follow-up calls

Urine Specimen Collection

Undergo urine sample collection at baseline

Silicone Wrist Band

Non-smoking family/household members will wear a silicone wristband for 2 days at each assessment for ancillary studies

Interview

Selected participants will take part in an interview for ancillary studies

Focus Group

Participants will review and comment on materials under development to be used in randomized clinical trial.

Primary outcome measure

  • Proportion of participants who have quit smoking at 6 months [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Edgar Yu

877-827-3222edgar.yu@ucsf.edu

Locations

University of California, San Francisco

Recruiting

San Francisco, California, United States, 94143

Contacts

Edgar Yu

edgar.yu@ucsf.edu

877-827-3222cancertrials@ucsf.edu

Principal Investigator:

Janice Tsoh, PhD

More Information

Sponsor

University of California, San Francisco

Last update posted

Jun 4, 2026

Last verified

May, 2026

Keywords

  • Third-hand Smoke

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-06-04.