Recruiting

VR vs. HFA

Sponsor:

Nova Scotia Health Authority

Code:

NCT07063537

Conditions

Glaucoma Open-Angle

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Virtual Reality Visual Field (VR-VF)

Study Details

Brief summary:

The goal of this clinical trial is to evaluate the feasibility of using virtual reality based visual field testing to monitor glaucoma in a clinical setting. This will be done through comparison of a virtual reality (VR) based device to the current gold standard Ziess Humphrey Field Analyzer (HFA). The main questions the study aims to answer are:

  • Can both devices produce similar results in terms of detecting visual field defects and progression?
  • Does the stage (early, moderate, advanced) of glaucoma impact results between the two devices?

Participants will perform both a standard and a VR based visual field test at each visit, for a total of 5 visits.

Conditions

Glaucoma Open-Angle

Study ID

NCT07063537

Start date

Dec 14, 2024

Status verified date

Jul, 2025

Completion date

Oct, 2025

Anticipated

Primary completion date

Oct, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • >18 years of age
  • diagnosis of primary open-angle glaucoma
  • ability to perform visual field testing
  • capacity to provide informed consent to research protocol

Exclusion Criteria:

  • diagnosis of secondary glaucoma or non-glaucomatous optic neuropathy
  • previous intraocular surgery (excluding cataract surgery and minimally invasive glaucoma surgery)
  • significant media opacity
  • pregnancy
  • seizure disorder
  • cardiac pacemaker/other implantable device
  • severe vertigo/balance disorder

Study Design

Enrollment

60 participants

Anticipated

Intervention Model

Single group

Primary purpose

Diagnostic

Interventions and Outcome Measures

Arms

experimental: Visual Field Testing

Participants will perform both a virtual reality-based visual field test and a standard Humphrey visual field test for both eyes.

Interventions

Virtual Reality Visual Field (VR-VF)

Both devices administer a standard visual field test. The Humphrey is the gold standard desk top model and the VR-VF is a virtual reality headset designed to deliver visual field testing

Primary outcome measure

  • Visual field point-wise threshold values [ Time Frame: Measured during each visual field test on visits 1 through 5 (throughout study completion, average 2 months) ]
  • Global indices of visual field loss [ Time Frame: Measured during each visual field test on visits 1 through 5 (throughout study completion, average 2 months) ]
  • Reliability Indices [ Time Frame: Measured during each visual field test on visits 1 through 5 (throughout study completion, average 2 months) ]

Central Contacts and Locations

Central contacts

Reann Post, BSc

19029560601reann.post@dal.ca

Lynn Murphy

19024072380lynn@eadietech.com

Locations

Eadie Technologies Inc

Recruiting

Halifax, Nova Scotia, Canada, B3L1N3

Contacts

Lynn Murphy

19024072380lynn@eadietech.com

Reann Post, BSc

9029560601reann.post@dal.ca

Principal Investigator:

Brennan Eadie, MD, PhD, FRCSC

More Information

Sponsor

Nova Scotia Health Authority

Last update posted

Jul 14, 2025

Last verified

Jul, 2025

Keywords

  • Virtual Reality
  • Visual Field
  • Glaucoma

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Nova Scotia Health Authority on 2025-07-14.