Recruiting

CBT & Mindfulness

Sponsor:

The Chicago Lighthouse

Code:

NCT07073521

Conditions

Depression, Anxiety

Visual Impairment

Adjustment

Adjustment Disorder With Anxious Mood

Adjustment Disorder With Depressed Mood

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss

Study Details

Brief summary:

The goal of this study is to develop and pilot test a therapeutic strategy combining cognitive behavioral therapy (CBT) with mindfulness practices tailored for individuals adjusting to vision loss. The study will begin with focus groups to inform the design of the intervention. Participants will complete brief surveys on their background and experiences with vision loss prior to attending a focus group, and some may be invited to a second session to provide additional feedback before preliminary testing begins. In the pilot phase, participants will attend weekly group therapy sessions using the developed intervention and complete assessments before and after the program, including questions about vision status, demographics, and experiences with vision loss.

Conditions

Depression, Anxiety

Visual Impairment

Adjustment

Adjustment Disorder With Anxious Mood

Adjustment Disorder With Depressed Mood

Study ID

NCT07073521

Start date

Jul 14, 2025

Status verified date

Jul, 2025

Completion date

Jul 13, 2027

Anticipated

Primary completion date

Jul, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults who are at least 18 years old
  • Experiencing varying degrees of vision loss (e.g. mild, moderate, severe)
  • Willingness to participate in the focus group or pilot testing and provide feedback

Exclusion Criteria:

  • Individuals with severe cognitive impairment affecting participation
  • Congenital blindness
  • Recent or current participation in another clinical trial study or medical intervention that may interfere with study results
  • Documented or self-reported health condition that may interfere with the outcomes of this study.
  • Deemed unfit to participate in the study by the site investigator
  • Unwilling and/or unable to participate or provide consent

Study Design

Enrollment

45 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Pilot Testing - Assessing Feasibility and Acceptability

Participants will be testing an 8-week therapeutic strategy combining cognitive behavioral therapy (CBT) with mindfulness practices tailored for people adjusting to vision loss in a group therapy setting and complete assessments before and after completing the program.

Interventions

Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss

The intervention will be an 8-week integrated group therapy curriculum combining cognitive behavioral therapy (CBT) with mindfulness practices designed for individuals adjusting to vision loss.

Primary outcome measure

  • Change from Baseline in Mean Adaption to Vision Loss (AVL) Scale Score [ Time Frame: Assessed at baseline and following the 8-week intervention period ]

Central Contacts and Locations

Central contacts

Senior Research Associate

(312) 447-3254Research@chicagolighthouse.org

Locations

The Chicago Lighthouse

Recruiting

Chicago, Illinois, United States, 60608

Contacts

Senior Research Associate

312-447-3254Research@chicagoligthhouse.org

312-447-3234

Principal Investigator:

Chief Research Officer

More Information

Sponsor

The Chicago Lighthouse

Last update posted

Jul 30, 2025

Last verified

Jul, 2025

Keywords

  • Visually impaired
  • Blind
  • Vision loss
  • mental health
  • CBT
  • Cognitive-behavioral therapy (CBT)
  • mindfulness
  • adjustment to vision loss
  • focus group
  • pilot test
  • group therapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by The Chicago Lighthouse on 2025-07-30.