Recruiting

Cervical Cancer Screening

Sponsor:

University of Minnesota

Code:

NCT07075731

Conditions

Cancer Screening

Transgender

Gender Diverse Populations

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

No intervention

Study Details

Brief summary:

This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these tests in TGD individuals, and explore patient-centered options for these tests. By assessing the status of testing and correlation with hysterectomy pathology, this study will provide preliminary data on the current state of guideline-concordant care and provide initial evidence for the development of evidence-based guidelines in the future

Conditions

Cancer Screening

Transgender

Gender Diverse Populations

Study ID

NCT07075731

Start date

Jun 30, 2025

Status verified date

Jul, 2026

Completion date

Jun 30, 2027

Anticipated

Primary completion date

Jun 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 18 years and older
  • Able to provide voluntary written consent prior to the performance of any research related activity. Patients who can provide informed consent
  • Able to understand, speak, read, and write in English
  • Patients who have undergone hysterectomy, or plan to have a hysterectomy
  • Patients who are transgender and gender diverse"

Exclusion Criteria:

  • Opted out of research
  • <18 years old
  • Lacks capacity to consent/has diminished capacity to consent
  • Cannot provide informed consent
  • Those on the study's community advisory board

Study Design

Enrollment

40 participants

Anticipated

Interventions and Outcome Measures

Arms

Standard of Care Cancer Screening

FDA approved self swab

Mock self swab

Interventions

No intervention

Observational study

Primary outcome measure

  • Rates of cervical cancer screening and endometrial sampling in TGD individuals [ Time Frame: Month 36 ]
  • Whether HPV self-testing affects the rates of cervical cancer screening in TGD individuals [ Time Frame: Month 36 ]

Central Contacts and Locations

Central contacts

Samantha Hoffman, MD

(612)273-7117kehoe018@umn.edu

Locations

University of Minnesota

Recruiting

Minneota, Minnesota, United States, 55455

Contacts

Samantha Hoffman, MD

612-273-7117kehoe018@umn.edu

More Information

Sponsor

University of Minnesota

Last update posted

Jul 16, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Minnesota on 2026-07-16.