Recruiting

Observational Study

Sponsor:

Children's Hospital Los Angeles

Code:

NCT07084155

Conditions

Medication Adherence

Eligibility Criteria

Sex: All

Age: 15 - 20

Healthy Volunteers: Not accepted

Interventions

Adaptive Cell Phone Support

Study Details

Brief summary:

The goal of this feasibility pilot trial is to finalize the design of a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions. The main question\[s\] it aims to answer are:

1. Is the final version of the intervention sufficiently feasible, usable, and acceptable for evaluation in a randomized clinical trial?
2. Do participants show improvements in medication adherence during their field testing of the intervention?

Conditions

Medication Adherence

Study ID

NCT07084155

Start date

Mar 25, 2026

Status verified date

Jul, 2026

Completion date

Jan 31, 2027

Anticipated

Primary completion date

Jan 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 15 - 20

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Children's Hospital Los Angeles patient
  • between 15-20 years old at enrollment
  • taking at least one oral medication per day for a chronic health condition
  • English speaking
  • demonstrating sufficient cognitive capacity to engage in the assent/consent process and study procedures

There is no exclusion criteria.

Study Design

Enrollment

35 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Adaptive Cell Phone Support

Computer-delivered cell phone support (reminders, problem-solving, referrals to resources) and responsive human coaching (phone calls, test messages, in-app messaging) to improve medication adherence.

Interventions

Adaptive Cell Phone Support

Mobile health adherence promotion based on the supportive accountability model

Primary outcome measure

  • Total scores on the theoretical framework of acceptability questionnaire [ Time Frame: Baseline to 3 weeks ]
  • Mean scores on the Mobile Health App Usability Questionnaire [ Time Frame: Baseline to 3 weeks ]
  • Total scores on the Visual Analogue Scale [ Time Frame: Baseline to 3 weeks ]

Central Contacts and Locations

Central contacts

Caitlin Sayegh, PhD

323-361-7748cssayegh@chla.usc.edu

Locations

Children's Hospital Los Angeles

Recruiting

Los Angeles, California, United States, 90027

Contacts

Caitlin S Sayegh, PhD

323-361-7748cssayegh@chla.usc.edu

More Information

Sponsor

Children's Hospital Los Angeles

Last update posted

Jul 20, 2026

Last verified

Jul, 2026

Keywords

  • adolescents
  • mobile health
  • adherence

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Children's Hospital Los Angeles on 2026-07-20.