Recruiting

Genetic Testing

Sponsor:

UNC Lineberger Comprehensive Cancer Center

Code:

NCT07084168

Conditions

Ovary Cancer

Endometrial Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Educational videos

Survey

Study Details

Brief summary:

This pilot study aims to estimate rates of genetic testing in patients with ovarian and endometrial cancer before and after the implementation of educational videos about genetic testing. Subjects will be asked to view one of three videos relevant to their cancer diagnosis and genetic testing, and have the option to complete a brief satisfaction survey. A chart review to evaluate rates of genetic testing ordered and referrals placed to Genetics before and after the implementation of the videos will be conducted.

Up to 15-20% of ovarian cancer and 3-5% of endometrial cancer is due to inherited genetic mutation. Given this association, the National Comprehensive Cancer Network (NCCN) recommends genetic counseling and testing for all individuals with a diagnosis of ovarian cancer and endometrial cancer. Some challenges to obtaining genetic counseling and testing include missed identification and referral of eligible patients by providers, lack of provider knowledge, and busy clinic visits limiting time for informed consent and maintaining patient autonomy for genetic testing. Although heterogeneous, the literature supports multimedia use in cancer genetics. However, there is a paucity of data in the field of gynecologic oncology for the role of integrating a multimedia approach to genetic counseling.

Conditions

Ovary Cancer

Endometrial Cancer

Study ID

NCT07084168

Start date

Oct 10, 2024

Status verified date

Nov, 2025

Completion date

Oct 30, 2026

Anticipated

Primary completion date

Oct 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

In order to participate in this study, a subject must meet all of the eligibility criteria outlined below.

  • Reviewed informed consent to participate in the study.
  • Subject is willing and able to comply with study procedures based on the judgment of the investigator.
  • Age ≥ 18 years at the time of consent.
  • Diagnosis of ovarian cancer or endometrial cancer
  • Eligible for genetic testing
  • English or Spanish is the primary language

Exclusion Criteria:

  • Previously completed genetic testing
  • Did not receive initial cancer-directed treatment at study site

Study Design

Enrollment

30 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Genetic Testing Awarness

Educational videos about genetic testing will be provided for ovarian cancer and endometrial cancer.

Interventions

Educational videos

Educational videos about genetic testing will be provided. Subjects will be asked to view one of three videos (an endometrial cancer/Lynch Syndrome video or a longer or shorter version of an ovarian cancer video) relevant to their cancer diagnosis and genetic testing.

Survey

Subjects will be asked to complete a brief satisfaction survey.

Primary outcome measure

  • Proportion of genetic testing [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Locations

Univeristy of North Carolina at Chapel Hill

Recruiting

Chapel Hill, North Carolina, United States, 27599

Contacts

Principal Investigator:

Katherine Tucker, MD

More Information

Sponsor

UNC Lineberger Comprehensive Cancer Center

Last update posted

Nov 12, 2025

Last verified

Nov, 2025

Keywords

  • genetic testing
  • video implementation
  • chart review

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by UNC Lineberger Comprehensive Cancer Center on 2025-11-12.