Recruiting

Whole Food Plant-Based

Sponsor:

UCLA

Code:

NCT07090096

Conditions

Endometriosis

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Not accepted

Interventions

A whole food plant based diet

Study Details

Brief summary:

This randomized, controlled study will investigate the efficacy of a dietary intervention for women with endometriosis. Participants will be randomly assigned to follow a whole food plant-based (intervention) diet or stay on their usual (control) diet for 12 weeks.

Conditions

Endometriosis

Study ID

NCT07090096

Start date

Nov 1, 2025

Status verified date

Nov, 2025

Completion date

Oct 1, 2029

Anticipated

Primary completion date

Oct 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study visits, procedures, requirements, and availability for the duration of the study
3. Women with a surgical, imaging, or clinical diagnosis of endometriosis
4. Age 18-45 years
5. Stable health condition and medications for the past 3 months
6. Modified Biberoglu and Behrman (B\&B) pelvic pain score of at least 5/9
7. Willing to be randomly assigned to either an active or a control group
8. Agreement to adhere to Lifestyle Considerations throughout the study duration

Exclusion Criteria:

1. Smoking or drug abuse during the past six months
2. Alcohol consumption of more than 2 drinks per day or the equivalent, episodic increased drinking (e.g., more than 2 drinks per day on weekends), or a history of alcohol abuse or dependency followed by any current use
3. Already following a WFPB diet
4. Pregnant or breastfeeding, or plans of pregnancy within the study period
5. Hysterectomy or ovariectomy
6. Fibroids, ovarian cysts, pelvic inflammatory disease
7. Endocrine inflammatory conditions, such as Cushing's syndrome, Hashimoto's thyroiditis, Graves' disease, type 1 diabetes mellitus, and Addison's disease
8. Evidence of an eating disorder

Study Design

Enrollment

120 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Experimental arm which will receive the intervention

This group will receive the dietary intervention

no intervention: Control

This group with continue on their usual diet

Interventions

A whole food plant based diet

A whole food plant based (WFPB) diet

Primary outcome measure

  • Total pain score [ Time Frame: 12 weeks ]

Central Contacts and Locations

Central contacts

Locations

UCSD Health

Recruiting

La Jolla, California, United States, 92093

Contacts

More Information

Sponsor

University of California, San Diego

Last update posted

Apr 28, 2026

Last verified

Nov, 2025

Keywords

  • endometriosis, pain, quality of life, inflammatory markers, diet, nutrition

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Diego on 2026-04-28.