Recruiting
Phase 2

Chatbot Program

Sponsor:

Washington University School of Medicine

Code:

NCT07094503

Conditions

Body Image Disturbance

Disordered Eating Behaviors

Eating Disorder Prevention

Eligibility Criteria

Sex: All

Age: 13 - 19

Healthy Volunteers: Not accepted

Interventions

Wysa Digital Chatbot Program

Study Details

Brief summary:

The purpose of this study is to test an eating disorders prevention digital chatbot program in a diverse group of adolescents.

Conditions

Body Image Disturbance

Disordered Eating Behaviors

Eating Disorder Prevention

Study ID

NCT07094503

Start date

Jun 18, 2024

Status verified date

Jul, 2026

Completion date

Jul 30, 2027

Anticipated

Primary completion date

Jul 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 13 - 19

Healthy Volunteers: Not accepted

Inclusion Criteria

1. 13 - 19 years old
2. Owns a smartphone
3. Speaks English
4. US resident
5. Screens as at-risk for an eating disorder
6. Not currently in treatment for an eating disorder

Exclusion Criteria:

1. Below 13 or older than 19 years of age
2. Does not own a smartphone
3. Does not speak English
4. Lives outside the US
5. Screens as:

1. Having a subclinical or clinical ED
2. Not at risk for an ED
3. In treatment for an ED

Study Design

Enrollment

400 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Chatbot Intervention Condition

Participants receive access to the digital chatbot program featuring 5 CBT based modules for 3 months. Modules include psychoeducation and CBT-based exercises on regular eating and improving body image.

no intervention: Waitlist Control

Participants receive access to the digital chatbot program after 6 months and completion of the study.

Interventions

Wysa Digital Chatbot Program

Wysa is a digital rules-based chatbot program platform offering cognitive-behavioral therapy-based guided self-help modules, including five modules for eating and body image developed by our team. Participants in this arm will engage with the digital chatbot program daily for three months to complete all five modules.

Primary outcome measure

  • ED risk factors; Weight Concerns Scale [ Time Frame: 6 - months ]

Central Contacts and Locations

Central contacts

Mireya De Los Reyes, B.S/B.A.

314-935-5843mireya@wustl.edu

Marianna Mohr, B.S./B.A.

314-935-5843mariannamohr@wustl.edu

Locations

Washington University in St. Louis

Recruiting

St Louis, Missouri, United States, 63130

Contacts

Nathalie A Gullo, B.S./B.A.

314-935-5843Gullo@wustl.edu

Marianna Horton, B.S./B.A.

314-935-5843M.horton@wustl.edu

Principal Investigator:

Ellen E Fitzsimmons-Craft, PhD

More Information

Sponsor

Washington University School of Medicine

Last update posted

Jul 15, 2026

Last verified

Jul, 2026

Keywords

  • Adolescents
  • Disordered Eating Behaviors
  • Eating Disorder Symptoms
  • Eating Pathology
  • Eating disorder Prevention
  • Body Image
  • Body Image Disturbance
  • Digital Mental Health
  • Chatbot

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Washington University School of Medicine on 2026-07-15.