Recruiting

Smokeless Tobacco

Sponsor:

Roswell Park Cancer Institute

Code:

NCT07107139

Conditions

Smokeless Tobacco

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Interventions

Copenhagen group

Snus group

Study Details

Brief summary:

This study seeks to measure the effects of smokeless tobacco product risk messages on sensory experiences and future intentions to use.

Conditions

Smokeless Tobacco

Study ID

NCT07107139

Start date

May 11, 2026

Status verified date

May, 2026

Completion date

May 1, 2027

Anticipated

Primary completion date

May 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Age ≥ 21 years of age
  • Residing in 8 counties of Western NY (Erie, Niagara, Cattaraugus, Chautauqua, Allegheny, Livingston, Genesee, Orleans, Wyoming)
  • Smoke cigarettes every day, at least 5 cigarettes per day, for at least 1 year
  • Open to trying a non-combusted oral tobacco product
  • Have the ability to read, write, and communicate in English
  • Have successfully completed our preliminary Auction study I-4008824 with a bid for Copenhagen and/or General Snus > $0
  • Willing to abstain smoking 8-10 hours prior to each laboratory session and complete breath CO test for verification (<8ppm)
  • Female participants must be amenable to taking a pregnancy test (urine) prior to beginning study procedures.
  • Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure.

Exclusion Criteria:

  • Age ≥ 21 years of age
  • Residing in 8 counties of Western NY (Erie, Niagara, Cattaraugus, Chautauqua, Allegheny, Livingston, Genesee, Orleans, Wyoming)
  • Smoke cigarettes every day, at least 5 cigarettes per day, for at least 1 year
  • Open to trying a non-combusted oral tobacco product
  • Have the ability to read, write, and communicate in English
  • Have successfully completed our preliminary Auction study I-4008824 with a bid for Copenhagen and/or General Snus > $0
  • Willing to abstain smoking 8-10 hours prior to each laboratory session and complete breath CO test for verification (<8ppm) .
  • Female participants must be amenable to taking a pregnancy test (urine) prior to beginning study procedures.
  • Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure.

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Factorial

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

active comparator: Copenhagen group

Participants will place .66 grams of Copenhagen between cheek and gums for up to 30 minutes.

active comparator: Snus Group

Participants will place one pouch of snus beween cheek and gums for up to 30 minutes.

Interventions

Copenhagen group

Participants use product for up to 30 minutes

Snus group

Participants use product for up to 30 minutes

Primary outcome measure

  • Change in sensory response [ Time Frame: Before viewing study ads and immediatley after viewing ]

Central Contacts and Locations

Central contacts

ASK RPCI

1-877-275-7724askrpci@roswellpark.org

Locations

Roswell Park

Recruiting

Buffalo, New York, United States, 14263

Contacts

ask rpci

877-275-7724askrpci@roswellpark.org

Principal Investigator:

Richard O'Connor, PHD

More Information

Sponsor

Roswell Park Cancer Institute

Last update posted

May 22, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Roswell Park Cancer Institute on 2026-05-22.