Recruiting

Smart-Home Sensors

Sponsor:

University of Missouri-Columbia

Code:

NCT07120347

Conditions

Alzheimer Disease and Related Dementias (ADRD)

Mild Cognitive Impairment (MCI)

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Interventions

Remote Ambient Sensor System

Study Details

Brief summary:

The investigators aim to use smart-home sensors and artificial intelligence (AI) to monitor and detect Alzheimer's Disease and Related Dementias (ADRD)-specific daily activities among older adults, with the goal of early symptom detection and personalized support. Dementia, which impacts memory and cognition, remains a global concern. In the United States, more than 6.7 million individuals aged 65 and older are living with ADRD, and projected annual healthcare costs are expected to reach $1 trillion by 2050. This underscores the need for deeper understanding and innovative support. To address the unique challenges associated with ADRD, such as cognitive decline, personalized strategies that promote independent well-being are essential. Smart-home sensors can support older adults with ADRD as they continue to live in their homes. These sensors provide real-time data on health and daily activities, offering insights into their daily lives. However, adoption of these technologies is low, and the practical application of AI remains limited. This highlights the need for further research to make these devices more accessible to this population. The investigators' aims include:

Conducting focus groups with individuals with and without ADRD and their caregivers to identify daily activities that can be measured using in-home sensors; Collecting in-home sensor data from older adults with and without ADRD; and Using AI to develop a tool for recognizing daily activities. The integration of smart-home sensors with advanced data-analysis techniques holds significant potential for transforming the support and care provided to individuals with ADRD. Ultimately, the investigators' findings will contribute to improving the quality of life for affected individuals and alleviating the burden on caregivers and healthcare systems.

Conditions

Alzheimer Disease and Related Dementias (ADRD)

Mild Cognitive Impairment (MCI)

Study ID

NCT07120347

Start date

Aug 1, 2024

Status verified date

May, 2025

Completion date

Jul 31, 2027

Anticipated

Primary completion date

Jul 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Inclusion Criteria

  • Community-dwelling, English-speaking adults aged ≥ 50 years
  • Clinical diagnosis of mild cognitive impairment or mild dementia (ADRD)
  • Diagnosis established by a neuropsychologist, neurologist, or geriatrician within the University of Missouri Healthcare System
  • Diagnosis confirmed using the latest consensus criteria and verified through record review
  • No restriction on the etiology of the cognitive disorder (e.g., Alzheimer's disease, vascular dementia, mixed dementia)

Exclusion Criteria

  • Clinical Dementia Rating (CDR) global score > 1 (moderate or severe dementia)
  • Cognitive or functional impairments that would preclude meaningful participation in daily activities

Study Design

Enrollment

16 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Pariticpants w/ ADRD

active comparator: Participants w/o ADRD

Interventions

Remote Ambient Sensor System

Remote sensors (motion, door contact) deployed in participants' home connected through raspberry pi and mobile hotspot

Primary outcome measure

  • Classification accuracy of ambient sensor-based daily activity models [ Time Frame: Weeks 1-4 after enrollment ]
  • F1 score of ambient sensor-based daily activity models [ Time Frame: Weeks 1-4 after enrollment ]
  • Area under the ROC curve of ambient sensor-based daily activity models [ Time Frame: Weeks 1-4 after enrollment ]

Central Contacts and Locations

Central contacts

Locations

University of Missouri

Recruiting

Columbia, Missouri, United States, 65211

Contacts

More Information

Sponsor

University of Missouri-Columbia

Last update posted

Aug 13, 2025

Last verified

May, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Missouri-Columbia on 2025-08-13.