Recruiting
Phase 1
Phase 2

Resistance Exercise

Sponsor:

University of Florida

Code:

NCT07125378

Conditions

Mobility Limitation

Cognitive Impairment

Eligibility Criteria

Sex: All

Age: 65 - 70+

Healthy Volunteers: Not accepted

Interventions

Task-oriented resistance exercise

Study Details

Brief summary:

The purpose of the research is to evaluate the feasibility and benefits of a six-week hybrid task-oriented resistance exercise program for older adults who have been recently discharged from home health care.

Conditions

Mobility Limitation

Cognitive Impairment

Study ID

NCT07125378

Start date

Jan 6, 2026

Status verified date

Jan, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Nov 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 65 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • between the ages of 65 and 90 years
  • community-dwelling
  • live within a 50-mile radius of the study site with wireless connectivity in the area
  • mobility limitations as indicated by self-reported of using a mobility aid or having unsteady gait or walking slower than before
  • cognitive decline as indicated by a score < 12 on Mini MoCA Version 2.1
  • a care partner or adult family member living in the home or nearby
  • willing to wear an activity tracker during the study period

Exclusion Criteria:

  • plan to receive skilled rehabilitation services
  • plan to move away outside the study area in two months
  • reside in an assisted living or long-term care facility or plan to relocate to such a facility in the next three months
  • severe vision or hearing loss that impedes activity performance or communication
  • unable to stand or walk even with a mobility aid
  • unable to follow a one-step command or carry on a conversation over the phone
  • unable to commit to the six-week exercise program
  • contradictions to resistance exercise, such as the end-stage heart failure
  • a terminal disease or on hospice care
  • a neurological condition affecting motor skills
  • not able to provide consent.

Study Design

Enrollment

15 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: LIFT

Participants will receive a task-oriented resistance exercise program at home.

Interventions

Task-oriented resistance exercise

The intervention program includes progressive resistance exercise and daily activity exercise, delivered over a six-week period with an ideal frequency of three sessions per week. Progressive resistance exercise will be provided through a combination of in-person and online sessions, while daily activity exercise will be delivered exclusively in person.

Primary outcome measure

  • Short Physical Performance Battery [ Time Frame: Baseline, 8 weeks, and 12 weeks. ]
  • Montreal Cognitive Assessment [ Time Frame: Baseline, 8 weeks, and 12 weeks. ]

Central Contacts and Locations

Central contacts

Chiung-ju Liu Associate Professor, PhD

352-273-6496c.liu1@phhp.ufl.edu

Locations

College of Public Health and Health Professions, University of Florida

Recruiting

Gainesville, Florida, United States, 32610

Contacts

Chiung-ju Liu, PhD

352-273-6495c.liu1@phhp.ufl.edu

More Information

Sponsor

University of Florida

Last update posted

Jul 31, 2026

Last verified

Jan, 2026

Keywords

  • Home-based intervention
  • Exercise
  • Older adults
  • Activities of daily living
  • Mobility
  • Cognition

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Florida on 2026-07-31.