Recruiting

vCHE

Sponsor:

Mayo Clinic

Code:

NCT07126496

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Internet-Based Intervention

Questionnaire Administration

Virtual Technology Intervention

Study Details

Brief summary:

This clinical trial studies how well a virtual community health educator (vCHE) works in increasing clinical trial referrals for patients with cancer and their caregivers. Low enrollment of underrepresented and underserved populations in cancer clinical trials has led to disparities in intervention development and implementation. One approach to recruiting diverse populations to cancer clinical trials is community health educators. However, community health educator interventions are costly and difficult to implement. vCHEs are photo-realistic virtual agents that provide personalized guidance and support to users. They are designed to mimic real-life community health workers, offering culturally and linguistically tailored information to users. They can communicate in English or Spanish and are available in diverse genders and racial/ethnic backgrounds. vCHEs may be able to increase the enrollment of diverse participants into cancer clinical trials.

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Study ID

NCT07126496

Start date

May 20, 2025

Status verified date

Aug, 2026

Completion date

Aug 31, 2027

Anticipated

Primary completion date

Aug 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Individuals Diagnosed with Cancer

  • 18 years or older
  • Must have received a cancer diagnosis at any point in your life
  • Able to understand English or Spanish
  • Care Partners

  • Must be a care partner (also known as caregiver, carer, supporter, helper, aide, assistant, companion, attendant, advocate, or family caregiver) of an adult who has received a cancer diagnosis
  • Must be actively involved in the decision-making process OR care of a person diagnosed with cancer
  • Must be 18 years or older

Exclusion Criteria:

  • Self-reported: people who are currently or have been in a cancer clinical trial within the last 3 years

Study Design

Enrollment

2000 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Arm I (ALEX Research Portal, vCHE)

Participants receive information about available cancer clinical trials via the ALEX Research Portal and vCHE over 20-30 minutes on study.

active comparator: Arm II (online text)

Participants receive information about available cancer clinical trials via online text on study.

Interventions

Internet-Based Intervention

Receive information via online text

Questionnaire Administration

Ancillary studies

Virtual Technology Intervention

Receive information via ALEX Research Portal and vCHE

Primary outcome measure

  • Proportion of referrals to cancer clinical trials (CCTs) [ Time Frame: Up to 3 months ]
  • Number of patient referrals sent by a healthcare provider by using the ALEX portal [ Time Frame: Up to 3 months ]

Central Contacts and Locations

Central contacts

Enhancing Technology & Communication in Healthcare (ETCH) Lab

904-953-5375ETCH@mayo.edu

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Locations

Mayo Clinic in Florida

Recruiting

Jacksonville, Florida, United States, 32224-9980

Contacts

Principal Investigator:

Janice L. Krieger, PhD

More Information

Sponsor

Mayo Clinic

Last update posted

Aug 11, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-08-11.