Recruiting

Radiation Registry

Sponsor:

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Code:

NCT07129317

Conditions

Sarcoma

Pediatric Brain Tumors

Eligibility Criteria

Sex: All

Age: 0 - 26

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The Johns Hopkins Pediatric Radiation Oncology Program is creating a registry that will capture the full 3D radiation dosimetry delivered to its pediatric patients to manage the quality of care provided, as well as to examine the long-term outcomes and toxicity of each patient. The registry will capture baseline clinical data, disease, toxicity, and quality of life outcomes. The goal is to include all pediatric patients undergoing proton therapy and photon therapy to enable future comparisons of treatment outcomes.

Conditions

Sarcoma

Pediatric Brain Tumors

Study ID

NCT07129317

Start date

Oct 31, 2025

Status verified date

Nov, 2025

Completion date

Sep, 2040

Anticipated

Primary completion date

Sep, 2035

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 26

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Treatment with either proton or photon radiation therapy.

Exclusion Criteria:

  • Greater than 26 years old

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Arms

Pediatric brain tumors

Pediatric patients diagnosed with brain tumors requiring treatment with either proton or photon radiation therapy.

Pediatric sarcomas

Pediatric patients diagnosed with bone or soft tissue sarcomas requiring treatment with either proton or photon radiation therapy.

Non-brain-tumor and non-sarcoma

Primary outcome measure

  • Overall Survival [ Time Frame: Approximately 10 years ]
  • Toxicity due to Radiation Therapy as assessed by number of patients with adverse events [ Time Frame: Approximately 10 years ]

Central Contacts and Locations

Central contacts

Ethan Arnone, BS

2029192533earnone3@jh.edu

Betsy Sawdy, MSN

2029192551eburne10@jh.edu

Locations

Sibley Memorial Hospital

Recruiting

Washington D.C., District of Columbia, United States, 20016

Contacts

Ethan Arnone, BS

202-919-2533earnone3@jh.edu

Betsy Sawdy, MSN

eburne10@jh.edu

Principal Investigator:

Sahaja Acharya, MD

Johns Hopkins Hospital

Recruiting

Baltimore, Maryland, United States, 21287

Contacts

Ethan Arnone, BS

202-919-2533earnone3@jh.edu

Betsy Sawdy, MSN

eburne10@jh.edu

Principal Investigator:

Sahaja Acharya, MD

More Information

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Last update posted

Nov 5, 2025

Last verified

Nov, 2025

Keywords

  • Pediatric
  • Brain tumor
  • Registry
  • Proton radiation
  • Radiation therapy
  • Photon radiation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins on 2025-11-05.