Recruiting

SMART-3RP

Sponsor:

Zeba Ahmad, Ph.D.

Code:

NCT07139769

Conditions

Caregiving for Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Psychosocial Intervention for Parental Caregivers of AYA with Cancer

Study Details

Brief summary:

The study team aims to adapt a psychosocial intervention to reduce psychological distress among the caregiving parents of adolescents and young adults (aged 15-39) who have cancer. First, the study team will adapt an evidence-supported, group-based program for improving psychological resiliency (Stress Management and Resiliency Training - Relaxation Response Resiliency Program; SMART-3RP (E. R. Park et al., 2021)), and iteratively incorporate feedback from parents of AYAs with cancer using a mixed-methods approach. Next, the study team will pilot the refined intervention to assess for preliminary indicators of feasibility, acceptability, and potential for efficacy in reducing parental distress.

Conditions

Caregiving for Cancer

Study ID

NCT07139769

Start date

Sep, 2026

Status verified date

Aug, 2026

Completion date

Jan, 2027

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Self-identifying parent/guardian who provides a primary informal caregiving role in their child's cancer
  • Recipient of caregiving is aged between 15 and 39 years and is receiving treatment for cancer at the Mass General Brigham Cancer
  • Participant must score equal to or greater than 2 (out of a possible 10) on the National Comprehensive Cancer Network Distress Thermometer
  • English-speaking
  • Aged over 18 years

Exclusion Criteria:

-Active symptoms of psychosis or suicidal ideation that would preclude safe participation

Study Design

Enrollment

48 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Psychosocial Intervention for Parental Caregivers of AYA with Cancer-open pilot study

The study team aims to evaluate the feasibility and acceptability of the adapted psychosocial intervention to 1) improve psychological resiliency to stress and 2) reduce symptoms of depression, anxiety, and post-traumatic stress among parental caregivers, through a single-arm open pilot trial of 32 parents.

Interventions

Psychosocial Intervention for Parental Caregivers of AYA with Cancer

A new adaptation of an evidence-supported intervention, the SMART-3RP program, to address psychological symptoms and promote well-being among parental caregivers of AYA with cancer.

Primary outcome measure

  • Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll [ Time Frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months) ]
  • Intervention Feasibility: Proportion of Participants Completing the Program [ Time Frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months) ]
  • Intervention Acceptability [ Time Frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months) ]

Central Contacts and Locations

Central contacts

Zeba N Ahmad, Ph.D.

16177241586zahmad2@mgh.harvard.edu

Katana Corning, B.A.

6177247593kcorning@mgh.harvard.edu

Locations

Mass General Brigham Cancer Institute at Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Zeba Ahmad, Ph.D.

631-786-0403zahmad7@gmail.com

Principal Investigator:

Zeba N Ahmad, Ph.D.

More Information

Sponsor

Zeba Ahmad, Ph.D.

Last update posted

Aug 25, 2026

Last verified

Aug, 2026

Keywords

  • adolescents and young adults with cancer
  • cancer caregivers

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Zeba Ahmad, Ph.D. on 2026-08-25.