Recruiting

Neurosurgical Procedure

Sponsor:

Jacobs institute

Code:

NCT07140731

Conditions

Moyamoya Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Symani Surgical System

Study Details

Brief summary:

A research study for a neurosurgical procedure in adult patients with Moyamoya disease

Conditions

Moyamoya Disease

Study ID

NCT07140731

Start date

Sep 20, 2025

Status verified date

Oct, 2025

Completion date

Sep 1, 2027

Anticipated

Primary completion date

Sep 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Patients aged >18.
2. Moyamoya disease with minor to moderate symptoms requiring neurosurgical treatment.
3. Patients agree to have the surgery and the anesthesia.
4. Patients who voluntarily decide to participate in this study with the surgery performed with the aid of Symani and agree to sign the Informed Consent Form.

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Exclusion Criteria:

1. Patients who have bleeding or coagulation disorders in the past or present.
2. Any criteria that preclude prolonged anesthesia.
3. Hemodynamically unstable neurological exam.
4. Pressure dependent neurologic status.

Study Design

Enrollment

15 participants

Anticipated

Intervention Model

Single group

Primary purpose

Device Feasibility

Interventions and Outcome Measures

Arms

experimental: Single arm study with neurosurgical procedure

To assess the safety and effectiveness of the Symani Surgical System

Interventions

Symani Surgical System

To assess the safety and effectiveness of the Symani Surgical System

Primary outcome measure

  • CT Imaging [ Time Frame: 6 Months ]

Central Contacts and Locations

Central contacts

CARLOS PENA, PhD, MS

17168884814cpena@jacobsinstitute.org

Locations

Jacobs Institute

Recruiting

Buffalo, New York, United States, 14203

More Information

Sponsor

Jacobs institute

Last update posted

Oct 16, 2025

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Jacobs institute on 2025-10-16.