Recruiting

Bone Marrow

Sponsor:

Ossium Health, Inc.

Code:

NCT07145411

Conditions

Bone Marrow Transplant (BMT)

Eligibility Criteria

Sex: All

Age: 12 - 70+

Healthy Volunteers: Not accepted

Interventions

Bone Marrow Transplant with Ossium's HPC, Marrow (bone marrow recovered from deceased organ and tissue donors)

Study Details

Brief summary:

Ossium recognizes that not all patients who could benefit from Ossium's HPC, Marrow can access the PRESERVE trial for logistical or eligibility reasons. The HOPE program is expanded access program to serve these patients by providing our bone marrow product

Conditions

Bone Marrow Transplant (BMT)

Study ID

NCT07145411

Start date

Jun 27, 2024

Status verified date

Aug, 2025

Completion date

Aug, 2029

Anticipated

Primary completion date

Aug, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 12 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Patients aged 12-80 may be eligible\* to receive bone marrow for transplantation through the Ossium HOPE Program if:

Their treating physician determined they are eligible for allogeneic bone marrow transplant Their treating physician determined that the potential benefit outweighs the potential risks

Study Design

Enrollment

10 participants

Anticipated

Interventions and Outcome Measures

Arms

Ossium HPC, Marrow

Ossium HPC, Marrow will be provide for infusion on the day of transplant

Interventions

Bone Marrow Transplant with Ossium's HPC, Marrow (bone marrow recovered from deceased organ and tissue donors)

The HOPE Program does not include any investigational drugs. The medicines and procedures in this program are standard of care for a transplant. Bone marrow cells from a deceased organ and tissue donor for use in your transplant is the only product offered to you by Ossium Health.

Primary outcome measure

  • Neutrophil engraftment [ Time Frame: 28 days ]

Central Contacts and Locations

Central contacts

Preethi Prasad, Senior Director Clinical Operations

415-513-5535preethi.prasad@ossiumhealth.com

Locations

University of Alabama, Birmingham

Recruiting

Birmingham, Alabama, United States, 35294

Henry Ford Health

Recruiting

Detroit, Michigan, United States, 48202

The Ohio State University Medical Center

Recruiting

Columbus, Ohio, United States, 43210

Tristar Centennial Medical Center

Recruiting

Nashville, Tennessee, United States, 37203

More Information

Sponsor

Ossium Health, Inc.

Last update posted

Aug 28, 2025

Last verified

Aug, 2025

Keywords

  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Lymphomas
  • Chronic lymphoblastic Leukemia
  • Chronic Myeloid Leukemia
  • myelodysplastic syndrome
  • stem cell transplant
  • severe aplastic anemia
  • Sickle cell anemia
  • Thalessemia

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Ossium Health, Inc. on 2025-08-28.