Recruiting

Pink & Pearl Campaign

Sponsor:

Washington University School of Medicine

Code:

NCT07146568

Conditions

Lung Cancer

Cancer of the Lung

Eligibility Criteria

Sex: All

Age: 20+

Healthy Volunteers: Accepted

Interventions

Pink and Pearl Campaign

Study Details

Brief summary:

Inspired by the ongoing Pink \& Pearl Campaign, the breast radiology service of Christian Hospital in north St. Louis County will partner with Siteman Cancer Center to pilot this campaign in its mammography clinics in order to promote awareness, referral, and completion of lung cancer screening (LCS) among eligible women. This campaign leverages established infrastructure such as nurse navigation and referral to screening or primary care for further shared decision-making on cancer screening. The purpose of this study is to evaluate the effectiveness of the Pink \& Pearl Campaign in improving LCS uptake among LCS-eligible women undergoing mammography at Christian Hospital. This evaluation is grounded in the Integrated Screening Action Model that depicts individual- and environmental-level influences on the screening behavior process. Using an explanatory sequential mixed methods design, which combines both quantitative and qualitative approaches, our specific aims for this proposal are to: a) assess whether the Pink \& Pearl Campaign increases referrals and uptake/completion of LCS among LCS-eligible women undergoing screening mammography; b) determine median time-to-screening after referral to LCS; and c) evaluate individual and health system factors influencing LCS uptake and implementation outcomes of the campaign. These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating cancer screening programs to improve poorly performing programs like LCS.

Conditions

Lung Cancer

Cancer of the Lung

Study ID

NCT07146568

Start date

Feb 23, 2026

Status verified date

Aug, 2026

Completion date

Feb 28, 2027

Anticipated

Primary completion date

Feb 28, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 20+

Healthy Volunteers: Accepted

Eligibility Criteria - Interventional Study

  • Undergoing screening mammography at Christian Hospital
  • Between the ages of 50-80 years (inclusive)

Eligibility Criteria - Survey and Interview Sub-Studies

  • Part of the interventional study
  • Reporting a 20 pack-year equivalent of either current smoking history or have quit in the past 15 years
  • Can speak and understand English
  • Not diagnosed with a serious health problem that will limit life expectancy (such as previous history of lung cancer, symptoms of lung cancer such as hemoptysis or unexplained weight loss of more than 6.8 kg (15 lb) in the previous year)
  • Willing and able to get treatment if lung cancer is found
  • Able to understand and willing to sign an IRB-approved written informed consent document

Eligibility Criteria - Providers

  • At least 20 years of age
  • Involved in the breast radiology service or referred at least one patient to the Pink \& Pearl Campaign
  • Able to provide verbal consent to participate in the interview

Study Design

Enrollment

5515 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Screening

Interventions and Outcome Measures

Arms

experimental: Participants - scheduled for mammography and eligible for LCS

All women coming in for breast cancer screening will be assessed for LCS eligibility using a screening questionnaire administered by mammography technicians. Patients who are determined to be eligible for LCS will be asked by the mammography technician if they will opt into being contacted by the nurse navigator, who will facilitate their referral to primary care to schedule a LCS appointment at Siteman Cancer Center.

no intervention: Providers

Providers in the breast radiology service who referred women to LCS. Investigators will gather information on the feasibility, acceptability, and appropriateness of the Pink and Pearl project.

Interventions

Pink and Pearl Campaign

This campaign leverages established infrastructure such as nurse navigation and referral to screening or primary care for further shared decision-making on cancer screening.

Primary outcome measure

  • Proportion of women referred from the breast radiology service who successfully complete LCS 6-months post-Pink & Pearl implementation [ Time Frame: At 6 months ]

Central Contacts and Locations

Central contacts

Beryne Odeny, M.D., MPH, Ph.D.

314-362-1183beryne@wustl.edu

Locations

Barnes-Jewish Christian Hospital

Recruiting

St Louis, Missouri, United States, 63136

Contacts

Beryne Odeny, M.D. MPH, Ph.D.

314-362-1183beryne@wustl.edu

Principal Investigator:

Beryne Odeny, M.D., MPH, Ph.D.

More Information

Sponsor

Washington University School of Medicine

Last update posted

Aug 12, 2026

Last verified

Aug, 2026

Keywords

  • Lung cancer screening (LCS)
  • Pink and Pearl Campaign
  • Breast cancer screening (BCS)
  • Low-dose computed tomography (LDCT)
  • Smoking history
  • Health disparities
  • Screening behavior
  • Feasibility
  • Acceptability
  • Appropriateness

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Washington University School of Medicine on 2026-08-12.