Recruiting

Yoga & Mindfulness

Sponsor:

Barbara Nemesure

Code:

NCT07161713

Conditions

Cancer Survivors

Cancer Survivorship

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Oncology-informed yoga

SMART

Study Details

Brief summary:

Cancer survivors can experience health issues that cause chronic illness and lower quality of life. Yoga is a well-known holistic approach to health and overall well-being. Mindfulness has many benefits, including improved focus and less stress. This study aims to evaluate if yoga and/or mindfulness has a positive effect on cancer survivors social, emotional and physical well-being as well as their epigenetics. Epigenetics is how the environment can effect your genes; not by changing our DNA, but by turning genes on or off.

Conditions

Cancer Survivors

Cancer Survivorship

Study ID

NCT07161713

Start date

Sep 17, 2025

Status verified date

Jul, 2026

Completion date

Sep 30, 2027

Anticipated

Primary completion date

Sep 17, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults over 18 years old
  • Primary diagnosis: Lung Cancer, Colon Cancer and Non-Hodgkin's lymphoma (NHL)
  • Six months post cancer-directed treatment (chemotherapy, targeted and immunotherapy). Patients with active disease (e.g. metastatic colorectal cancer) who are not receiving any cancer-directed treatment are eligible.
  • Able to provide a saliva sample
  • Gives informed consent and agrees to be randomly assigned
  • Able to complete the questionnaire(s) in English.

Exclusion Criteria:

  • Adults with primary anal and/or primary rectal cancer.
  • Adult cancer survivors who are currently on an active treatment regimen.
  • Oral or any pathological conditions that can limit the ability to produce saliva.
  • Unable to participate in full length study period and follow up thereafter.
  • Is pregnant or plan to become pregnant during the study period.
  • Currently practicing yoga or SMART
  • Those on corticosteroid therapy.
  • Documented fall or syncope within the last 6 months

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Yoga

Oncology-informed yoga

experimental: SMART

Stress Management and Resiliency Training

Interventions

Oncology-informed yoga

8 weekly sessions of cancer informed-yoga incorporating light movement, breathing techniques, and some meditation practices

SMART

SMART, developed by the Impact Foundation, is an adaptation of Mindfulness-based Stress Reduction (MBSR) approach that incorporates other elements like mindful self-compassion, emotional literacy, and positive psychology principles to address the unique stressors faced by teachers.

Primary outcome measure

  • Patient Reported Quality of Life (QOL) by EORTC QLQ-C30 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by EORTC QLQ-SURV100 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-ANL27 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-BIL21 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-BN20 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-BR42 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-CLL17 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-CR29 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-CX24 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-EN24 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-GINET21 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-HCC18 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by EORTC QLQ-HL27 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by EORTC QLQ-HN43 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-LC29 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by EORTC QLQ-LMC21 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-MY20 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-NHL-HG29 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) by QLQ-NHL-LG20 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-OES18 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-OG25 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-OV28 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-PR25 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-STO22 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-TC26 [ Time Frame: 8 weeks ]
  • Patient Reported Quality of Life (QOL) QLQ-THY34 [ Time Frame: 8 weeks ]

Central Contacts and Locations

Central contacts

Stony Brook Cancer Center Clinical Trials

631-728-7425CancerClinicalTrials@stonybrookmedicine.edu

Chitra Thakur, PhD

(631)-216-9086Chitra.Thakur@stonybrookmedicine.edu

Locations

Stony Brook University Cancer Center

Recruiting

Stony Brook, New York, United States, 11794

Contacts

Ravi Kanani

(631)-572-1923Ravikumar.Kanani@stonybrookmedicine.edu

Caterina Vacchi-Suzzi, PhD

631-216-2993caterina.vacchi-suzzi@stonybrookmedicine.edu

Principal Investigator:

Barbara Nemesure, PhD

More Information

Sponsor

Barbara Nemesure

Last update posted

Jul 20, 2026

Last verified

Jul, 2026

Keywords

  • stony brook
  • survivor
  • yoga
  • mindfulness-based stress reduction
  • holistic
  • stress management
  • cancer survivor
  • long island
  • mindfulness
  • cancer
  • EORTC
  • questionnaires
  • surveys

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Barbara Nemesure on 2026-07-20.