Recruiting

Flavor Perceptions

Sponsor:

University of Oklahoma

Code:

NCT07162935

Conditions

Cigar Smoking

Tobacco Use

Eligibility Criteria

Sex: All

Age: 18 - 24

Healthy Volunteers: Accepted

Interventions

Cigarillo brand 1

Cigarillo brand 2

Cigarillo brand 3

Study Details

Brief summary:

This clinical trial will recruit young adults who currently use cigarillos and examine the smoking behavior and perceptions of different flavored cigarillos, product ingredients/additives impacting these perceptions, and simulated tobacco use outcomes (quitting, switching) in various policy scenarios where different types of flavors are available on the market.

Conditions

Cigar Smoking

Tobacco Use

Study ID

NCT07162935

Start date

Feb 23, 2026

Status verified date

May, 2026

Completion date

May 31, 2030

Anticipated

Primary completion date

Mar 2, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 24

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Ages 18 to 24
2. Report past 30-day use of a cigarillo
3. Ability to read English at least an 8th grade level
4. No immediate plans to quit using tobacco
5. At least 1 prior experience with a flavored tobacco product
6. U.S. Citizen or permanent resident of the United States.

Exclusion Criteria:

1. Current use of smoking cessation pharmacotherapy or nicotine replacement therapy;
2. Pregnant, planning to become pregnant, or currently breastfeeding;
3. Past or current clinically significant heart disease or hypertension, or other smoking-related disease that could preclude successful study completion;
4. Inability to abstain from nicotine/tobacco products for at least 12 hours
5. Unwillingness to use the research cigarillos in the lab

Study Design

Enrollment

300 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Concept flavor

Participants will be randomized to smoke one of the three assigned concept flavored cigarillos

experimental: Characterizing flavor

Participants will be randomized to smoke one of the three assigned characterizing flavored cigarillos

experimental: Tobacco flavor

Participants will be randomized to smoke a tobacco flavored cigarillo

Interventions

Cigarillo brand 1

Participants will be assessed on puffing behavior, subjective effects, and exhaled carbon monoxide when assigned to using one of three cigarillo brands. Additives and ingredients of the cigarillo used will also be assessed

Cigarillo brand 2

Participants will be assessed on puffing behavior, subjective effects, and exhaled carbon monoxide when assigned to using one of three cigarillo brands. Additives and ingredients of the cigarillo used will also be assessed

Cigarillo brand 3

Participants will be assessed on puffing behavior, subjective effects, and exhaled carbon monoxide when assigned to using one of three cigarillo brands. Additives and ingredients of the cigarillo used will also be assessed

Primary outcome measure

  • Puff number [ Time Frame: From enrollment to the end of the final smoking visit, approximately 2 weeks ]
  • Subjective reward from smoking [ Time Frame: From enrollment to the end of the final smoking visit, approximately 2 weeks ]

Central Contacts and Locations

Central contacts

Project Manager

405-271-7759heal-lab@ouhsc.edu

Locations

University of Oklahoma Health Campus

Recruiting

Oklahoma City, Oklahoma, United States, 73104

Contacts

Amy Cohn Principal Investigator, PhD

405-271-7759heal-lab@ouhsc.edu

More Information

Sponsor

University of Oklahoma

Last update posted

May 11, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Oklahoma on 2026-05-11.