Recruiting

BumptUp

Sponsor:

Old Dominion University

Code:

NCT07166822

Conditions

Cardiovascular (CV) Risk

Exercise

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Interventions

Experimental group using BumptUp mobile exercise app

Study Details

Brief summary:

The goal of this study is to determine the effectiveness of a mobile exercise app in improving cardiovascular health and motivation to exercise in pregnant women who are healthy, in their 2nd trimester, between 18-45 years age, and do not do exercise currently. The aims of this study are determine i) the effect of a mobile app (BumptUp) to increase motivation to exercise as assessed by questionnaire, and ii) the changes may occur in cardiovascular health outcomes such as increased percent Flow-Mediated Dilation (FMD), Heart Rate Variability (HRV), and decreased Pulse Wave Velocity (PWV) over an 8-week period of intervention. Researchers will compare this to pregnant women who are healthy, in their 2nd trimester, between 18-45 years age, and who will not be using the mobile app (BumptUp) for exercise. Participants who are in the experimental group will be given access to the mobile app (BumptUp) for 8 weeks. Both the control and experimental group will visit the lab for their baseline measurements (study visit 1), followed by two visits at 4 weeks (study visit 2) and 8 weeks (study visit 3) to have their heart rate variability, arterial stiffness (PWV), and vascular function (FMD) assessed. At each study visit, blood pressure, heart rate, height, and weight will also be measured. Additionally, at all three study visits, participants will fill out a questionnaire to determine motivation to exercise.

Conditions

Cardiovascular (CV) Risk

Exercise

Study ID

NCT07166822

Start date

Sep 15, 2025

Status verified date

Sep, 2025

Completion date

Aug 1, 2028

Anticipated

Primary completion date

Aug 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 45

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Age: 18-45 years.
  • Pregnant women who are 20-24 weeks pregnant at enrollment
  • Sedentary, as defined by completing less than 90 minutes of exercise each week.
  • Generally healthy, uncomplicated pregnancies.
  • Free of physical limitations that may interfere with alterations in daily physical activity levels.
  • Single gestation.
  • Have a smartphone
  • Under the routine medical care of an obstetrician or certified nurse midwife during their current pregnancy.
  • Women speaking English.

Exclusion Criteria:

  • Physician diagnosed cardiovascular/ vascular complications (heart disease, high blood pressure, Raynaud's phenomenon etc.)
  • Physician diagnosed metabolic diseases (diabetes, hypothyroidism)
  • Musculoskeletal injuries (broken bones, back pain, ankle sprain, muscle pull, etc.)
  • Medications that may impact blood vessel function such as hypertension medication (Angiotensin converting enzyme inhibitor, Angiotensin receptor blocker, Calcium channel blocker, beta blocker), lipid lowering agents (statins), Nitrates, steroids, etc.
  • Complications associated with pregnancy that would be exacerbated by exercise such as lung disease, persistent spotting/bleeding or Placental Previa, premature labor, ruptured membranes, evidence of intrauterine growth restriction, pregnancy induced hypertension or pre-eclampsia, uncontrolled epileptic fits/seizures.
  • Smoking within the previous 3 months.

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Experimental arm who will use the BumptUp mobile exercise app

This group will have access to "BumptUp" mobile exercise app and will be provided with an educational brochure (Exercise during pregnancy)

no intervention: Control group

This group will have no access to "BumptUp" mobile exercise app and will only be provided with an educational brochure (Exercise during pregnancy)

Interventions

Experimental group using BumptUp mobile exercise app

This BumptUp app has been developed specifically for pregnancy with safety and screening feature. This intervention will be unique since the researchers will evaluate the cardiovascular health outcomes following the 8 weeks of intervention.

Primary outcome measure

  • Flow mediated dilation [ Time Frame: 8 weeks of intervention period ]

Central Contacts and Locations

Central contacts

Principal Investigator, PhD

757-683-4974lreynold@odu.edu

Locations

Old Dominion University

Recruiting

Norfolk, Virginia, United States, 23529

Contacts

Principal investigator, PhD

757-239-7889lreynold@odu.edu

More Information

Sponsor

Old Dominion University

Last update posted

Sep 10, 2025

Last verified

Sep, 2025

Keywords

  • pregnant
  • cardiovascular
  • mobile app
  • exercise

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Old Dominion University on 2025-09-10.