Recruiting

RSV Vaccine

Sponsor:

UCLA

Code:

NCT07171164

Conditions

Older Adults Without Any Specific Clinical Condition

Social Networks

RSV Immunization

Vaccine Uptake

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Motivate Aim: CHW text message reminders and counseling

Motivate Aim: CHW text message reminders only

Activate Aim: CHW text message reminders and counseling

Activate Aim: CHW text message reminders only

Study Details

Brief summary:

In collaboration with community-based organizations, this study will focus on increasing RSV vaccine use among Latinos. The study will determine how effective community health worker counseling and text-message approaches are to (1) increase RSV vaccine use among older adults (Motivate phase) and (2) encourage younger adults to discuss RSV vaccination with their older friends and family members (Activate phase).

Conditions

Older Adults Without Any Specific Clinical Condition

Social Networks

RSV Immunization

Vaccine Uptake

Study ID

NCT07171164

Start date

Sep 10, 2025

Status verified date

Sep, 2025

Completion date

Nov, 2028

Anticipated

Primary completion date

Nov, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Motivate Aim Inclusion Criteria:

  • Age 50 years or older
  • Self-identify as Latino/a/x and/or indigenous groups from Latin America
  • Eligible for RSV vaccination per current CDC/ACIP recommendations
  • Fluent in Spanish or English
  • Has not received the RSV vaccine
  • Has a cell phone
  • Lives or works in San Francisco or Daly City
  • Able to provide informed consent

Motivate Aim Exclusion Criteria:

  • Intent to move outside of San Francisco or Daly City in the next year
  • Nursing home resident
  • Household member participating in Aim 1 or 2
  • Unable to provide consent

Motivate Aim Inclusion Criteria:

  • Age 18-49 years
  • Self-identify as Latino/a/x and/or indigenous groups from Latin America
  • Fluent in English or Spanish
  • Has >1 family member or friend 50 years or older who they have seen or spoken to for >15 minutes in the last 6 months and who lives in the United States

Activate Trial Exclusion Criteria:

  • Household member enrolled in Aim 1 or 2
  • Unable to provide consent

Study Design

Enrollment

750 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Motivate Aim: CHW text message reminders and counseling

active comparator: Motivate Aim: CHW text message reminders only

experimental: Activate Aim: CHW text message reminders and counseling

active comparator: Activate Aim: CHW text message reminders only

Interventions

Motivate Aim: CHW text message reminders and counseling

Participants receive both text message reminders and a counseling session, along with information about RSV and the vaccine, to encourage RSV vaccine uptake.

Motivate Aim: CHW text message reminders only

Participants receive text message reminders along with information about RSV and the RSV vaccine to encourage vaccine uptake, but do not receive the counseling intervention

Activate Aim: CHW text message reminders and counseling

Participants receive both text message reminders and a counseling session, along with information about RSV and the vaccine, to encourage discussion of RSV vaccine uptake among older adults in their social networks

Activate Aim: CHW text message reminders only

Participants receive text message reminders along with information about RSV and the vaccine to encourage discussion of RSV vaccine uptake among older adults in their social networks, but do not receive the counseling intervention

Primary outcome measure

  • Motivate Aim Primary Outcome - RSV Vaccine Uptake [ Time Frame: 60 days from study enrollment ]
  • Activate Aim Primary Outcome - Proportion of Contacts with whom RSV Vaccination Discussed [ Time Frame: 60 days after study enrollment ]

Central Contacts and Locations

Central contacts

RSV Uptake Study Coordinator

415-608-8339informatevrs@ucsf.edu

Locations

University of California, San Francisco

Recruiting

San Francisco, California, United States, 94110

Contacts

RSV Uptake Study Coordinator

415-608-8339informatevrs@ucsf.edu

More Information

Sponsor

University of California, San Francisco

Last update posted

Sep 30, 2025

Last verified

Sep, 2025

Keywords

  • RSV
  • RSV vaccine
  • Social networks
  • Counseling
  • Healthy adults

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-22. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2025-09-30.