Recruiting

Observational Study

Sponsor:

University of Arizona

Code:

NCT07173257

Conditions

Pancreas Neoplasms

Pancreatitis

Pancreatic Cyst

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The standard of care for a patient with resectable pancreatic is to perform pancreatic resection which, even in the modern era is associated with significant complications and impact on quality of life, often in the setting of poor survival even in the best scenario. Currently, there is a lack of data on patient quality of life after such procedures, how quality of life changes throughout the course of care, and whether patients who undergo these procedures are satisfied with their decision. This research is aimed to understand the impact of pancreatic surgery on patients' quality of life, how that impact changes over time, and patient satisfaction (or regret) with their decisions. This work will help improve the pre-operative conversation to help patients decide whether undergoing a pancreatic resection aligns with their post-operative goals of care.

Conditions

Pancreas Neoplasms

Pancreatitis

Pancreatic Cyst

Study ID

NCT07173257

Start date

Apr 3, 2023

Status verified date

Sep, 2025

Completion date

Dec, 2026

Anticipated

Primary completion date

Dec, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients >18 years old who undergo pancreatic resection for any indication of any race, gender, or ethnicity who are fluent in English

Exclusion Criteria:

  • <18 years old
  • Deemed not to have capacity to consent.

Study Design

Enrollment

250 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Change from Baseline in Quality of Life Measured by EORTC QLQ-C30 Scale up to 24 Months Post-Operatively [ Time Frame: Baseline, Immediately Post-Op, 3, 6, 12, 18, and 24 months after surgery ]
  • Change from Baseline in European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Pancreatic Cancer Module (EORTC QLQ-PAN26) Subscale Scores up to 24 Months Post-Operatively [ Time Frame: Baseline, Immediately Post-op, 3, 6, 12, 18, and 24 months after surgery ]

Central Contacts and Locations

Locations

Mayo Clinic - Phoenix

Recruiting

Phoenix, Arizona, United States, 85054

Contacts

Principal Investigator:

Zhi V. Fong, MD, MPH

The University of Arizona

Recruiting

Tucson, Arizona, United States, 85724

Contacts

Principal Investigator:

Taylor S. Riall, MD, PhD

More Information

Sponsor

University of Arizona

Last update posted

Sep 15, 2025

Last verified

Sep, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Arizona on 2025-09-15.