Recruiting

ACLP

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT07179809

Conditions

Metastatic Breast Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Demographics/Lifestyle Survey

Study Details

Brief summary:

The research study is to learn how the ACLP can best support patients with stable HR+/HER2- MBC.

Conditions

Metastatic Breast Cancer

Study ID

NCT07179809

Start date

Aug 21, 2026

Status verified date

Aug, 2026

Completion date

Oct 1, 2029

Anticipated

Primary completion date

Oct 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Patients with HR+/HER2 negative MBC
2. On first- or second-line treatment
3. Life expectancy at least 12 months
4. Only females
5. Age 18 years or older
6. Able to read, write, and speak English
7. Willingness to follow protocol requirements
8. Have a smartphone with access to cellular service or computer access with internet service
9. Oriented to person, place, and time
10. Consume less than 3 servings of fruit and vegetable/day
11. Engage in less than 150 minutes moderate/vigorous intensity activity per week, defined as anything that causes small increases in breathing or heart rate for a sustained amount of time (e.g., brisk walking, bicycling)
12. Engage in a mind-body practice less than 4 times a month

Exclusion Criteria:

1. Another primary cancer diagnosis within past 5 years (not including non-melanoma skin cancers)
2. Any major thought disorder (e.g., schizophrenia, dementia)
3. Communication barriers (e.g., hard of hearing)
4. Poorly-controlled or uncontrolled diabetes in the opinion of the physician(s)
5. Extreme mobility issues (e.g., unable to get in and out of a chair unassisted)

Study Design

Enrollment

100 participants

Anticipated

Allocation

Non randomized

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: ACLP Program

Participants will take part in the ACLP alone

experimental: ACLP Program + Learning Circles

Participants will take part in the ACLP and Learning Circles

experimental: ACLP Program + Learning Circles + Individual Health Coaching

Participants will take part in the ACLP and in Learning Circles After participants complete the ACLP with Learning Circles, they will receive up to 6 individualized health coaching sessions.

Interventions

Demographics/Lifestyle Survey

Participants will complete all sessions and instruments

Primary outcome measure

  • Safety and Adverse Events (AEs) [ Time Frame: Through study completion; an average of 1 year. ]

Central Contacts and Locations

Central contacts

Locations

The University of Texas M. D. Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Principal Investigator:

Meroe Morse, MD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Aug 31, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-08-31.