Recruiting

Observational Study

Sponsor:

University of Michigan

Code:

NCT07180628

Conditions

Stutter

Stuttering, Adult

Stuttering

Stuttering, Developmental

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

Speech Production During functional magnetic resonance imaging (MRI)

Study Details

Brief summary:

The overall objective of this study is to examine inter effector areas (IEAs) activity and functional connectivity during continuous speech production in stuttering adults.

Conditions

Stutter

Stuttering, Adult

Stuttering

Stuttering, Developmental

Study ID

NCT07180628

Start date

Apr 24, 2026

Status verified date

Apr, 2026

Completion date

Mar, 2029

Anticipated

Primary completion date

Mar, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Are between the ages of 18-65 years
  • Have otherwise normal speech, language, hearing and cognition
  • Speak English as their primary language
  • Currently stutter

Exclusion Criteria:

  • Have serious medical or neurological conditions (e.g., stroke, traumatic brain injury, Parkinson's disease, etc.)
  • Have had a closed head injury (e.g., concussion)
  • Have a reading disorder (e.g., dyslexia)
  • Have hearing loss
  • Have metal or electronic implants (e.g., cochlear implants, pacemakers, etc.)
  • Are currently pregnant

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Stutter group

Participants that stutter

Interventions

Speech Production During functional magnetic resonance imaging (MRI)

Participants will complete a speech production task with 2 conditions (stuttered, non-stuttered) while undergoing functional MRI to assess brain activity. Brain activity will be compared within subjects for the 2 conditions. The intervention is the combination of tasks delivered to all participants. The speaking task is the intervention (modifying agent) and the MRI is a measurement tool, not a therapeutic or modifying agent.

Primary outcome measure

  • Blood-Oxygen-Level-Dependent (BOLD) signal change during speaking [ Time Frame: During the speech task (5 runs, 8 minutes each) distributed across MRI Visits 1-6, up to 12 months from enrollment. ]

Central Contacts and Locations

Central contacts

Emily Garnett, PhD

734-232-3371emilyog@umich.edu

Locations

University of Michigan

Recruiting

Ann Arbor, Michigan, United States, 48109

Contacts

Emily Garnett, PhD

734-232-3371emilyog@umich.edu

Principal Investigator:

Soo-Eun Chang, PhD

More Information

Sponsor

University of Michigan

Last update posted

Apr 29, 2026

Last verified

Apr, 2026

Keywords

  • Magnetic Resonance Imaging (MRI) scans
  • Behavioral assessments

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Michigan on 2026-04-29.