Recruiting

Laparoscopic Clamps

Sponsor:

The University of Texas Health Science Center, Houston

Code:

NCT07182045

Conditions

Myoma

Surgery

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Interventions

Temporary clamping of uterine and ovarian vessels

Study Details

Brief summary:

This study hypothesizes that temporary bilateral uterine and utero-ovarian artery occlusion with laparoscopic clamps at time of minimally invasive myomectomy will lead to a decreased blood loss at time of myomectomy compared to minimally invasive myomectomy without temporary occlusion.

Conditions

Myoma

Surgery

Study ID

NCT07182045

Start date

Sep 18, 2025

Status verified date

May, 2026

Completion date

Sep 30, 2029

Anticipated

Primary completion date

Sep 30, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Patient undergoing minimally invasive myomectomy with either a single intramural or Submucosal fibroid =/>5cm or
  • Patients undergoing minimally invasive Myomectomy with =/> 5 fibroids

Exclusion Criteria:

  • Pregnancy,
  • Age <18yo,
  • Patients undergoing concomitant surgery such as endometriosis surgery,
  • Suspected malignancy

Study Design

Enrollment

120 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Temporary vessel clamps

Use of temporary laparoscopic vessel clamps on uterine and ovarian vessels

no intervention: No Temporary vessel clamps

No use of vessel clamps

Interventions

Temporary clamping of uterine and ovarian vessels

Surgeon will temporarily clamp uterine and ovarian vessels.

Primary outcome measure

  • Estimated blood loss [ Time Frame: Intraoperative (during surgery, which is < 24 hours) ]

Central Contacts and Locations

Central contacts

Randa Jalloul, MD

3137128603randa.j.jalloul@uth.tmc.edu

Locations

Memorial Hermann Hospital

Recruiting

Houston, Texas, United States, 77030

Contacts

Randa Jalloul, MD

713-486-7700randa.j.jalloul@uth.tmc.edu

More Information

Sponsor

The University of Texas Health Science Center, Houston

Last update posted

May 14, 2026

Last verified

May, 2026

Keywords

  • myoma
  • blood loss

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by The University of Texas Health Science Center, Houston on 2026-05-14.