Recruiting

Telerehabilitation

Sponsor:

VA Office of Research and Development

Code:

NCT07190365

Conditions

Mild to Moderate Traumatic Brain Injury

Cognitive Rehabilitation

Veteran

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

GOALS TH

EDU TH

Study Details

Brief summary:

Provision of interventions that address cognitive and emotional problems faced by Veterans with history of TBI pursuing community reintegration is an important concern for VA. Using telerehabilitation, the current project will help determine whether goal-directed training of attentional control functions via personally relevant activities will improve community integration for Veterans with history of TBI and cognitive difficulties. Findings may guide rehabilitation training towards providing services to maximize success in attaining complex functional goals in which Veterans can engage in skill strengthening 'where they are' (any location).

Conditions

Mild to Moderate Traumatic Brain Injury

Cognitive Rehabilitation

Veteran

Study ID

NCT07190365

Start date

Apr 1, 2026

Status verified date

Apr, 2026

Completion date

Mar 30, 2030

Anticipated

Primary completion date

Mar 30, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • History of mild to moderate TBI > 6 months ago
  • Cognitive difficulties affecting daily functioning
  • Age 18-65
  • Veteran
  • At least 12th grade education or equivalent \* Interested in improving community reintegration

Exclusion Criteria:

  • Amnesic/Severe memory problems
  • Active Substance Abuse/Dependence
  • Medical condition that may affect mental status/disrupt study participation
  • Active psychotropic medication changes

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: GOALS TH

The Goal-Oriented Attentional Self-regulation training involves ten 2-hour sessions of group-based telehealth training, three individual 1-hour telehealth training sessions, and approximately 20 hours of home practice. It is conducted in a small group format.

active comparator: EDU TH

The EDU TH training is an active control training matched with GOALS TH for therapist time, homework load, and participation in a group. It involves ten 2-hour telehealth sessions of group-based training, three individual 1-hour telehealth training sessions, and approximately 20 hours of home practice.

Interventions

GOALS TH

The Goal-Oriented Attentional Self-regulation training involves ten 2-hour sessions of group-based telehealth training, three individual 1-hour telehealth training sessions, and approximately 20 hours of home practice. It is conducted in a small group format.

EDU TH

The EDU TH training is an active control training matched with GOALS TH for therapist time, homework load, and participation in a group. It involves ten 2-hour telehealth sessions of group-based training, three individual 1-hour telehealth training sessions, and approximately 20 hours of home practice.

Primary outcome measure

  • Neurocognitive performance -Overall Attention and Executive Function (AEF) Z score [ Time Frame: Baseline, 10 week (post training), 6 month ]

Central Contacts and Locations

Central contacts

Tatjana Novakovic-Agopian, PhD

(415) 753-3888tatjana.novakovic-agopian@va.gov

Locations

VA Palo Alto Health Care System, Palo Alto, CA

Recruiting

Palo Alto, California, United States, 94304-1207

Contacts

Aman Kumar

650-493-5000Aman.Kumar@va.gov

Geoffrey W Goodale, BS

(518) 626-5626Geoffrey.Goodale@va.gov

Principal Investigator:

Tatjana Novakovic-Agopian, PhD

More Information

Sponsor

VA Office of Research and Development

Last update posted

Apr 3, 2026

Last verified

Apr, 2026

Keywords

  • Mild to Moderate Traumatic Brain Injury
  • Cognitive Rehabilitation
  • Telehealth
  • Community Reintegration

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by VA Office of Research and Development on 2026-04-03.