Recruiting

Observational Study

Sponsor:

Indiana University

Code:

NCT07195357

Conditions

Dentin Hypersensitivity

Erosive Tooth Wear

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

epidemiological

Study Details

Brief summary:

The goal of this observational study is to learn about tooth wear and tooth sensistivity and reasons for these conditions in five locations throughout the United States. The main question it aims to answer is:

The main objective of this study is to determine tooth wear and tooth sensitivity in adults in the U.S., and to investigate their association with risk factors

Conditions

Dentin Hypersensitivity

Erosive Tooth Wear

Study ID

NCT07195357

Start date

Feb 19, 2026

Status verified date

Feb, 2026

Completion date

Oct, 2027

Anticipated

Primary completion date

Oct, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Be aged 18 or over, of either gender.
2. Be attending a regularly scheduled appointment at the dental school.
3. Provide voluntary, written informed consent.
4. Understand and be willing, able and likely to comply with all study procedures and restrictions.
5. Be in good health (see exclusion criteria below).
6. Have a minimum of 10 teeth not including implants or teeth with crowns or bridges.

Exclusion Criteria:

1. Have any medical condition that could be expected to interfere with the subject's safety during the study period (including temporomandibular disorders).
2. Be incapable of responding to the questions.
3. Be an employee or a family relative of an employee of the sponsor.
4. Be using maxillary or mandibular orthodontic appliances, except lingual bar.
5. Have used analgesic (pain relieving) drugs or have used a topical analgesic in the preceding 12 h

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Arms

Adults age 18 living in five different areas of the United States

The five areas are Indiana, Florida, California, Texas and North Carolina

Interventions

epidemiological

collection of data from all participating subjects involving tooth erosion examinations, tooth sensitivity and questionnaire data collection

Primary outcome measure

  • Prevalence and severity of erosive tooth wear (ETW), assessed using the basic erosive wear examination (BEWE) index. [ Time Frame: Five minute examination period ]
  • Prevalence and severity of dentin hypersensitivity (DH) using the Schiff Sensitivity Index. [ Time Frame: Five minute examination period ]
  • Risk factors potentially associated to erosive tooth wear (ETW) and dentin hypersensitivity (DH), collected by questionnaires. [ Time Frame: Ten minutes assessment period. ]

Central Contacts and Locations

Central contacts

Anderson Hara, MS, PhD

317 274 8822ahara@iu.edu

Locations

Indiana University School of Dentistry - Oral Health Research Institute

Recruiting

Indianapolis, Indiana, United States, 46202

Contacts

Anderson T Hara, DDS, MSD, PhD

(317) 274-8822ahara@iu.edu

Lorena galvez, crc

(317)274-8822logalvez@iu.edu

More Information

Sponsor

Indiana University

Last update posted

May 5, 2026

Last verified

Feb, 2026

Keywords

  • erosive tooth wear
  • ETW
  • Dentin hypersensitivity
  • DH
  • Tooth Sensitivity
  • Dental Erosion

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Indiana University on 2026-05-05.