Recruiting

ERVs & PACs

Sponsor:

The University of Texas at Arlington

Code:

NCT07196436

Conditions

Asthma Control

Pulmonary Function

Quality of Life

Stress

Sleep Quality

Eligibility Criteria

Sex: All

Age: 5+

Healthy Volunteers: Not accepted

Interventions

Energy Recovery Ventilator

Portable Air Cleaner

Energy Recovery Ventilator (Sham)

Portable Air Cleaner (Sham)

Study Details

Brief summary:

The primary goal of this study is to investigate the comparative long-term (i.e., 1-year) effectiveness of energy recovery ventilators (ERVs) and portable air cleaners (PACs) in reducing indoor air pollutants and mold levels and improving asthma-related health outcomes in inner-city children and adults with asthma in low-income households in the Dallas-Fort Worth (DFW) metropolitan area, TX. Secondary goals include: (1) examining associations among asthma outcomes, exposure to indoor air pollutants and mold, and housing-related factors, (2) conducting a cost-benefit analysis of ERV and PAC interventions for improving IAQ, mold control, and health outcomes, and (3) evaluating the utility of cost-effective methods and protocols for measuring IAQ and mold for indoor air pollution epidemiology studies and for providing practical information to patients and their physicians. Using a double-blind, placebo-controlled randomized controlled trial, 80 households will be assigned to receive active or placebo versions of ERVs or PACs. Environmental exposures and housing conditions will be monitored alongside comprehensive health assessments, including lung function tests and validated surveys on asthma control, quality of life, stress, and sleep quality.

Conditions

Asthma Control

Pulmonary Function

Quality of Life

Stress

Sleep Quality

Study ID

NCT07196436

Start date

Oct 10, 2025

Status verified date

Oct, 2025

Completion date

Feb 28, 2028

Anticipated

Primary completion date

Jan 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 5+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Individuals with physician-diagnosed asthma, including both adults and children aged 5-17
  • Homeowners living in the DFW metropolitan area, TX

Exclusion Criteria:

  • Participants living in homes with any smokers

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Active ERV

A group that will receive an active energy recovery ventilator for 1 year

sham comparator: Sham ERV

A group that will receive a sham energy recovery ventilator (recirculation mode only) for 1 year

active comparator: Active PAC

A group that will receive an active portable air cleaner for 1 year

sham comparator: Sham PAC

A group that will receive a sham portable air cleaner (HEPA filter removed) for 1 year

Interventions

Energy Recovery Ventilator

A mechanical ventilation system that exchanges stale indoor air with fresh outdoor air while transferring heat and moisture between the incoming and outgoing air streams

Portable Air Cleaner

A standalone home device that filters indoor air to remove particulate matter, allergens, and other pollutants

Energy Recovery Ventilator (Sham)

A home-installed ERV unit that operates in recirculation mode only, providing no fresh air exchange or heat/moisture transfer, serving as a placebo for study purposes.

Portable Air Cleaner (Sham)

A portable air cleaner that appears to operate like an active unit but does not contain a HEPA filter and does not clean the air, serving as a placebo for study purposes

Primary outcome measure

  • Pulmonary Function (Spirometry) [ Time Frame: Baseline; 6 months; 18 months; 24 months ]
  • Asthma Control Test Score [ Time Frame: From enrollment to the end of intervention at 1 month (24 months in total) ]

Central Contacts and Locations

Central contacts

Locations

University of Texas at Arlington

Recruiting

Arlington, Texas, United States, 76010

Contacts

Rebuilding Together North Texas

Recruiting

Plano, Texas, United States, 75025

Contacts

More Information

Sponsor

The University of Texas at Arlington

Last update posted

Oct 29, 2025

Last verified

Oct, 2025

Keywords

  • Asthma
  • Asthma Control
  • Pulmonary Function
  • Lung Function
  • Quality of Life
  • Stress
  • Sleep Quality
  • Indoor Air Quality
  • Residential Ventilation
  • Air Cleaner
  • Air Filtration
  • Mold

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-20. This information was provided to ClinicalTrials.gov by The University of Texas at Arlington on 2025-10-29.