Recruiting

Group Therapy

Sponsor:

University of Nebraska

Code:

NCT07200531

Conditions

Chronic Stress

Eligibility Criteria

Sex: Female

Age: 19 - 54

Healthy Volunteers: Accepted

Interventions

Psychotherapy

Study Details

Brief summary:

The goal of this clinical trial is to learn if group therapy for six weeks changes the gut microbiome in women. The main questions it aims to answer are:

Is chronic stress associated with the gut microbiome? Will six weeks of therapy change the gut microbiota?

Participants will:

Answer questionnaires about chronic stress Mail a stool sample before and after the intervention. Participate in a 1-hour group therapy session over the course of six weeks.

Conditions

Chronic Stress

Study ID

NCT07200531

Start date

Dec 1, 2025

Status verified date

Dec, 2025

Completion date

Jul, 2026

Anticipated

Primary completion date

Apr, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 19 - 54

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Women over the age of 19 and less than 54. Able to understand/read English

Exclusion Criteria:

  • Pregnant women and breast-feeding women Women who are actively participating in psychotherapy on a regular basis

Study Design

Enrollment

30 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Psychotherapy Intervention

Interventions

Psychotherapy

6-week psychotherapy group intervention

Primary outcome measure

  • Depression, Anxiety, and Stress Scales [ Time Frame: 6 weeks ]
  • Perceived Stress [ Time Frame: 6 weeks ]

Central Contacts and Locations

Central contacts

Ashley J Blount, PhD

4025596613ablount@unomaha.edu

Tiffany A Moore, PhD, RN

4025596613tamoore@unmc.edu

Locations

University of Nebraska Medical Center

Recruiting

Omaha, Nebraska, United States, 68198

Contacts

Tiffany Moore

402-559-6613mamamicrobiome@unmc.edu

More Information

Sponsor

University of Nebraska

Last update posted

Mar 25, 2026

Last verified

Dec, 2025

Keywords

  • Gut Microbiome
  • Life-course trauma
  • Psychotherapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Nebraska on 2026-03-25.